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2011 Fiscal Year Final Research Report

the novel non pharmaceutical therapy for patients with chronic renal failure using low temperature sauna

Research Project

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Project/Area Number 21500505
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Rehabilitation science/Welfare engineering
Research InstitutionKumamoto Health Science University

Principal Investigator

IIYAMA Junichi  熊本保健科学大学, 保健科学部, 教授 (00398299)

Co-Investigator(Renkei-kenkyūsha) KITAMURA Kenichirou  熊本大学, 医学部附属病院, 講師 (10304990)
Project Period (FY) 2009 – 2011
Keywords温熱療法 / 低温サウナ / 慢性腎不全 / 一酸化窒素 / 血管内皮機能
Research Abstract

We have been investigating about the effects of low temperature sauna for renal failure using the mice of 5/6 renal extracted model. Although we firstly intended to use rats, we decided to use mice because of its usefulness as gene knocked out model. Our plan has been delayed due to taking many days to create the suitable renal failure model. We will try to make the evidences of low temperature sauna therapy for renal failure in the near future.

  • Research Products

    (26 results)

All 2011 2010 2009 Other

All Journal Article (15 results) (of which Peer Reviewed: 15 results) Presentation (8 results) Remarks (1 results) Patent(Industrial Property Rights) (2 results) (of which Overseas: 2 results)

  • [Journal Article] 温熱の消化器・腎・皮膚への影響2011

    • Author(s)
      飯山準一
    • Journal Title

      Japanese Journal of Rehabilitation Medicine

      Volume: vol.48(1) Pages: 28-32

    • Peer Reviewed
  • [Journal Article] Proteolytic activation of ENaC and therapeutic application of a serine protease inhibitor for the treatment of salt-sensitive hypertension2011

    • Author(s)
      Kitamura, K., Tomita, K
    • Journal Title

      Clin. Exp. Nephrol

      Volume: 16(1) Pages: 44-8

    • Peer Reviewed
  • [Journal Article] A case of anti-glomerular basement membrane antibody-induced glomerulonephritis with cytomegalovirus-induced thrombotic microangiopathy2011

    • Author(s)
      Shiraishi, N., Kitamura, K., Tomita, K., et al
    • Journal Title

      Intern. Med. J.

      Volume: 76(4) Pages: 266-72

    • Peer Reviewed
  • [Journal Article] A study of maintenance therapy after intravenous maxacalcitol for secondary hyperparathyroidism2011

    • Author(s)
      Adachi, M., Tomita, K., Kitamura, K
    • Journal Title

      Clin. Nephrol

      Volume: 76 Pages: 266-272

    • Peer Reviewed
  • [Journal Article] Cys34 on antioxidative propertie of HSA quantitative analysis of cysteine-34 on the anitioxidative properties of human serum albumin in hemodialysis patients2011

    • Author(s)
      Anraku, M., Kitamura, K., Tomita, K., et al
    • Journal Title

      J. Pharm. Sci

      Volume: 100 Pages: 3968-3976

    • Peer Reviewed
  • [Journal Article] Regulation of renal sodium handling through the interaction between serine proteases and serine protease inhibitors2010

    • Author(s)
      Kitamura, K. and Tomita, K.
    • Journal Title

      Clim. Exp. Nephrol

      Volume: 14 Pages: 405-10

    • Peer Reviewed
  • [Journal Article] Regulation of adrenal aldosterone production by serine protease prostasin2010

    • Author(s)
      Ko, T., Tomita, K., Kitamura, K., et al
    • Journal Title

      J. Biomed. Biotech

      Pages: 793843

    • Peer Reviewed
  • [Journal Article] Human sodium-phosphate transporter 4(hNPT4/SLC17A3) as a common renal secretory pathway for drugs and urate2010

    • Author(s)
      Jutabha, P., Kitamura, K., Tomita, K., et al
    • Journal Title

      J. BIOL. Chem

    • Peer Reviewed
  • [Journal Article] Aberrant ENaC activation in Dahl salt-sensitive rats2009

    • Author(s)
      Kakizoe, Y., Kitamura, K., Tomita, K., et al
    • Journal Title

      J. Hypertens

      Volume: 27 Pages: 1679-1689

    • Peer Reviewed
  • [Journal Article] Urinary prostasin in humans : relationships among prostasin, aldosterone and epithelial sodium channel activity2009

    • Author(s)
      Koda, A., Tomita, K., Kitamura, K., et al
    • Journal Title

      Hypertens. Res

      Volume: 32 Pages: 267-281

    • Peer Reviewed
  • [Journal Article] Camostat mesilate inhibits prostasin activity, and reduces blood pressure and renal injury in salt-sensitive hypertension2009

    • Author(s)
      Maekawa, A., Tomita, K., Kitamura, K., et al
    • Journal Title

      J. Hypertens

      Volume: 27 Pages: 181-189

    • Peer Reviewed
  • [Journal Article] Calreticulin positively regulates the expression and function of epithelial sodium channel2009

    • Author(s)
      Sugahara, T., Kitamura, K., Tomita, K., et a
    • Journal Title

      Exp Cell Res

      Volume: 315 Pages: 3294-3300

    • Peer Reviewed
  • [Journal Article] Improvements in limb kinetic apraxia by repetition of a newly designed facilitation exercise in a patient with corticobasal degeneration2009

    • Author(s)
      Kawahira K, Noma T, Iiyama J, Etoh S, Ogata A, Shimodozono M.
    • Journal Title

      Int J Rehabil Res

      Volume: 32(2) Pages: 178-83

    • Peer Reviewed
  • [Journal Article] グリセリン添加強酸性浴による皮膚性状変化について2009

    • Author(s)
      飯山準一,川平和美
    • Journal Title

      日本温泉気候物理医学会雑誌

      Volume: 73(1) Pages: 44-45

    • Peer Reviewed
  • [Journal Article] 入浴による遺伝子転写、特異蛋白の誘導と免疫、臓器機能の変化入浴による肝・腎・腸管吸収機能の定量的分析2009

    • Author(s)
      飯山準一
    • Journal Title

      日本温泉気候物理医学会雑誌

      Volume: 73(1) Pages: 30

    • Peer Reviewed
  • [Presentation] Effects of the heat inhalation as a novel method of whole body warming in normal subjects2010

    • Author(s)
      Junichi Iiyama
    • Organizer
      第8回地中海リハビリテーション医学会
    • Place of Presentation
      ラルナカ(キプロス)
    • Year and Date
      2010-10-02
  • [Presentation] 『温泉・温熱の先端科学をリハビリテーションへ』温熱の消化器・腎・皮膚への影響2010

    • Author(s)
      飯山準一
    • Organizer
      日本リハビリテーション医学会学術集会
    • Place of Presentation
      鹿児島市
    • Year and Date
      2010-05-20
  • [Presentation] 熱吸入による経気道全身加温の試み2010

    • Author(s)
      宮崎慎二,飯山準一
    • Organizer
      第75回日本温泉気候物理医学会総会
    • Place of Presentation
      那須塩原市
    • Year and Date
      2010-05-15
  • [Presentation] Potentiality of thermal stimulation as a novel non pharmacological therapy on internal organs2009

    • Author(s)
      Junichi Iiyama
    • Organizer
      1st International Congress of Polish Rehabilitation
    • Place of Presentation
      Warszawa
    • Year and Date
      20090910-13
  • [Presentation] Effects of glycerin and strong acidic warm water bath on skin condition2009

    • Author(s)
      junichi iiyama, kazumi kawahira
    • Organizer
      5th World Congress of the International Society of Physical & Rehabilitation Medicine
    • Place of Presentation
      Istanbul, Turkey
    • Year and Date
      20090613-17
  • [Presentation] A study on the supply and demand of therapists in Japan2009

    • Author(s)
      junichi iiyama
    • Organizer
      5th World Congress of the International Society of Physical & Rehabilitation Medicine
    • Place of Presentation
      Istanbul, Turkey
    • Year and Date
      20090613-17
  • [Presentation] グリセリン添加入浴の長期使用に伴う臨床効果の変化2009

    • Author(s)
      岩下愛梨,林丈夫,飯山準一
    • Organizer
      第20回重症心身障害療育学会学術集会
    • Place of Presentation
      小樽市
    • Year and Date
      2009-10-05
  • [Presentation] グリセリン添加強酸性浴による皮膚性状変化について2009

    • Author(s)
      飯山準一,川平和美
    • Organizer
      第74回日本温泉気候物理医学会総会
    • Place of Presentation
      つくば市
    • Year and Date
      2009-05-15
  • [Remarks]

    • URL

      http://www.kumamoto-hsu.ac.jp/r-activity-list/r-activity-12.html

  • [Patent(Industrial Property Rights)] Thermotherapy and apparatus for thermotherapy2011

    • Inventor(s)
      飯山準一,川平和美
    • Industrial Property Rights Holder
      飯山準一,川平和美,ネクサス株式会社
    • Industrial Property Number
      F-10524 PCTU、S. Patent Appin. Serial No.61/302, 630
    • Filing Date
      2011-02-24
    • Overseas
  • [Patent(Industrial Property Rights)] Thermotherapy and apparatus for thermotherapy2011

    • Inventor(s)
      飯山準一,川平和美
    • Industrial Property Rights Holder
      飯山準一,川平和美,ネクサス株式会社
    • Industrial Property Number
      F-10524 PCTU、S. Patent Appin. Serial No.61/302, 630
    • Filing Date
      2011-02-24
    • Overseas

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Published: 2013-07-31  

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