2011 Fiscal Year Final Research Report
Development of the diagnostic method for periodontal diseases Using a microdevice to determine calprotectin
| Project/Area Number |
21592625
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Periodontal dentistry
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| Research Institution | The University of Tokushima |
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Principal Investigator |
KIDO Junichi 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 准教授 (10195315)
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| Co-Investigator(Kenkyū-buntansha) |
NAGATA Toshihiko 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 教授 (10127847)
BANDO Mikado 徳島大学, 病院, 医員 (10510000)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 歯周病診断 / カルプロテクチン / マイクロデバイス |
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| Research Abstract |
The purpose of this study is a development of a microdevice system to determine calprotectin in gingival crevicular fluid(GCF) with a small volume. We discharged an anti-calprotectin antibody on a microchip using an inkjet printing system and made the system to determine calprotectin in GCF using a microchip ELISA method. This method enabled to save GCF sample and antibody to one-fifty and a time one-five compared to a conventional ELISA method. This method to determine calprotectin in GCF may be useful for diagnosis of periodontal diseases.
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Research Products
(8 results)
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[Journal Article] Analysis of proteins in human gingival crevicular fluid by mass spectrometry2011
Author(s)
J Kido, M Bando, Y Hiroshima, H Iwasaka, K Yamada, N Ohgami, T Nambu, M Kataoka, T Yamamoto, Y Shinohara, I Sagawa, T Nagata
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Journal Title
DOI
Peer Reviewed
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