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2011 Fiscal Year Final Research Report

Effects of transcranial DC stimulation on cortico-basal ganglionic loop studied by fMRI, EEG and PET

Research Project

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Project/Area Number 21613003
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Non-invasive neuroimaging
Research InstitutionKyoto University

Principal Investigator

MIMA Tatsuya  京都大学, 医学研究科, 准教授 (20324618)

Co-Investigator(Renkei-kenkyūsha) SAWAMOTO Nobukatsu  京都大学, 医学研究科, 助教 (90397547)
MATSUHASHI Masao  京都大学, 医学研究科, 研究員 (40456885)
Project Period (FY) 2009 – 2011
Keywords経頭蓋的直流刺激法 / 脳可塑性 / 皮質基底核ループ
Research Abstract

Transcranial direct current stimulation(tDCS) was recently introduced in neuroscience and neurologic researches as one of the new brain stimulation techniques. In this research project, we investigated the brain mechanism of tDCS effects with special interests to cortico-basal ganglionic loop by using multimodal imaging. These findings enables us to study the tDCS effects from various perspectives and can lead to further researches in this field.

  • Research Products

    (47 results)

All 2011 2010 2009 Other

All Journal Article (13 results) (of which Peer Reviewed: 12 results) Presentation (33 results) Remarks (1 results)

  • [Journal Article] Differential contributions of theintraparietal sulcus and the in feriorparietal lobe to attentional blink : evidence from transcranial magneticstimulation2011

    • Author(s)
      Kihara K, Ikeda T, Matsuyoshi D, Hirose N, Mima T, Fukuyama H, Osaka N.
    • Journal Title

      J Cogn Neurosci

      Volume: 23 Pages: 247-56

    • DOI

      DOI:10.1162/jocn.2010.21426

    • Peer Reviewed
  • [Journal Article] Functional relevance of pre-supplementarymotor areas for the choice to stop duringStop signal task2011

    • Author(s)
      Tabu H, Mima T, Aso T, Takahashi R, Fukuyama H.
    • Journal Title

      Neurosci Res

      Volume: 70 Pages: 277-84

    • DOI

      DOI:10.1016/j.neures.2011.03.007

    • Peer Reviewed
  • [Journal Article] Momentary reward induce changes inexcitability of primary motor cortex2011

    • Author(s)
      Thabit MN, Nakatsuka M, Koganemaru S, Fawi G, Fukuyama H, Mima T.
    • Journal Title

      Clin Neurophysiol

      Volume: 122 Pages: 1764-70

    • DOI

      DOI:10.1016/j.clinph.2011.02.021

    • Peer Reviewed
  • [Journal Article] Effects of aging on the human motorcortical plasticity studied by pairedassociative stimulation2010

    • Author(s)
      Fathi D, Ueki Y, Mima T, Koganemaru S, Nagamine T, Tawfik A, Fukuyama H.
    • Journal Title

      Clin Neurophysiol

      Volume: 121 Pages: 90-3

    • DOI

      DOI:10.1016/j.clinph.2009.07.048

    • Peer Reviewed
  • [Journal Article] Recovery of upper-limb function due toenhanced use-dependent plasticity inchronic stroke patients Brain2010

    • Author(s)
      Koganemaru S, Mima T, Thabit MN, Ikkaku T, Shimada K, Kanematsu M, Takahashi K, Fawi G, Takahashi R, Fukuyama H, Domen K.
    • Volume
      133
    • Pages
      3373-84
    • DOI

      DOI:10.1093/brain/awq193

    • Peer Reviewed
  • [Journal Article] Movement-related cortical stimulation caninduce human motor plasticity2010

    • Author(s)
      Thabit MN, Ueki Y, Koganemaru S, Fawi G, Fukuyama H, Mima T.
    • Journal Title

      J Neurosci

      Volume: 25,30 Pages: 11529-36

    • DOI

      DOI:10.1523/JNEUROSCI.1829-10.2010

    • Peer Reviewed
  • [Journal Article] The neural correlates of endowment effect without economic transaction2010

    • Author(s)
      Votinov M, Mima T, Aso T, Abe M, Sawamoto N, Shinozaki J, Fukuyama H.
    • Journal Title

      Neurosci Res

      Volume: 68 Pages: 59-65

    • DOI

      DOI:10.1016/j.neures.2010.05.006

    • Peer Reviewed
  • [Journal Article] ブレイン・マシン・インターフェイス(BMI)と脳可塑性2010

    • Author(s)
      美馬達哉
    • Journal Title

      Monthly Book Medical Rehabilitation

      Volume: No.118 Pages: 59-65

  • [Journal Article] Suppression of human cortico-motoneuronalexcitability during the Stop-signal task Clin Neurophysiol2009

    • Author(s)
      Badry R, Mima T, Aso T, Nakatsuka M, Abe M, Fathi D, Foly N, Nagiub H, Nagamine T, Fukuyama H.
    • Volume
      120
    • Pages
      1717-23
    • DOI

      DOI:10.1016/j.clinph.2009.06.027

    • Peer Reviewed
  • [Journal Article] Stimulus-response profile duringsingle-pulse transcranial magneticstimulation to the primary motor cortex2009

    • Author(s)
      Hanakawa T, Mima T, Matsumoto R, Abe M, Inouchi M, Urayama S, Anami K, Honda M, Fukuyama H.
    • Journal Title

      Cereb Cortex

      Volume: 19 Pages: 2605-15

    • DOI

      DOI:10.1093/cercor/bhp013

    • Peer Reviewed
  • [Journal Article] Modulation of stimulus-induced 20-Hzactivity during lower extremity motorimagery2009

    • Author(s)
      Kinai T, Matsubayashi J, Minami C, Tominaga W, Nakamura M, Nagamine T, Matsuhashi M, Mima T, Fukuyama H, Mitani A
    • Journal Title

      Neurosci Res.

      Volume: 64 Pages: 335-7

    • DOI

      DOI:10.1016/j.neures.2009.03.013

    • Peer Reviewed
  • [Journal Article] Human motor associative plasticityinduced by paired bihemisphericstimulation2009

    • Author(s)
      Koganemaru S, Mima T, Nakatsuka M, Ueki Y, Fukuyama H, Domen K.
    • Journal Title

      J Physiol

      Volume: 587 Pages: 4629-44

    • DOI

      DOI:10.1113/jphysiol.2009.174342

    • Peer Reviewed
  • [Journal Article] A mirror reflection of a hand modulatesstimulus-induced 20-Hz activity2009

    • Author(s)
      Tominaga W, Matsubayashi J, Deguchi Y, Minami C, Kinai T, Nakamura M, Nagamine T, Matsuhashi M, Mima T, Fukuyama H, Mitani A.
    • Journal Title

      Neuroimage

      Volume: 46 Pages: 500-4

    • DOI

      DOI:10.1016/j.neuroimage.2009.02.021

    • Peer Reviewed
  • [Presentation] Emotion affects human motor corticalplasticity2011

    • Author(s)
      Koganemaru S, Mima T, Domen K, Fukuyama H
    • Organizer
      The 1st International Workshop on Synaptic Plasticity : from bench to bed side
    • Place of Presentation
      Taormina, Italy
    • Year and Date
      2011-04-01
  • [Presentation] Stroke, Damage, or Disease : Assessmentand Treatment2010

    • Author(s)
      Koganemaru S, Thabit M. H, Mima T, Domen K, Fukuyama H
    • Organizer
      The 40th Annual Meeting of the Society for Neuroscience
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2010-11-01
  • [Presentation] Human cortical response to parametricpassive finger movement2010

    • Author(s)
      Matsuhashi M, Mima T, Nagamine T, Shibasaki H, Fukuyama H
    • Organizer
      29th International Congress of Clinical Neurophysiology
    • Place of Presentation
      Kobe, Japan
    • Year and Date
      2010-11-01
  • [Presentation] Transcranial magnetic stimulation(TMS) and functional MRI2010

    • Author(s)
      Mima T
    • Organizer
      29th International Congress of Clinical Neurophysiology
    • Place of Presentation
      Kobe, Japan
    • Year and Date
      2010-11-01
  • [Presentation] Lettter recognition and human primarymotor cortex2010

    • Author(s)
      Nakatsuka M, Thabit MN, Koganemaru S, Mima T, Fukuyama H
    • Organizer
      29th International Congress of Clinical Neurophysiology
    • Place of Presentation
      Kobe, Japan
    • Year and Date
      2010-11-01
  • [Presentation] Parkinson's Disease : Dopamine and Non-Dopamine Pathways2010

    • Author(s)
      Ueki Y, Kawashima S, Matsukawa N, Ojika K, Kato T, Ito K, Mima T
    • Organizer
      The 40th Annual Meeting of the Society for Neuroscience
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2010-11-01
  • [Presentation] Long lasting effects of repeatedupper-limb extensor training combinedwith rTMS in chronic stroke patients2010

    • Author(s)
      Koganemaru S, Mima T, Thabit MH, Takahashi R, Fukuyama H
    • Organizer
      29th International Congress of Clinical Neurophysiology
    • Place of Presentation
      Kobe, Japan
    • Year and Date
      2010-10-01
  • [Presentation] Reorganization of motor system by repeatedupper-limb extensor trainings combinedwith rTMS in chronic stroke patients2010

    • Author(s)
      Koganemaru S, Mima T, Fukuyama H
    • Organizer
      NIPS/Sokendai Symposium "New Frontiers in Brain Sciences : Towards Systematic Understanding of Human Beings"
    • Place of Presentation
      Okazaki, Japan
    • Year and Date
      2010-10-01
  • [Presentation] Afferent inhibition of the motor evokedpotentials(combined study)2010

    • Author(s)
      Mima T
    • Organizer
      29th International Congress of Clinical Neurophysiology
    • Place of Presentation
      Kobe, Japan
    • Year and Date
      2010-10-01
  • [Presentation] Corticomotor plastic change induced bymirror therapy protocol2010

    • Author(s)
      Nojima I, Mima T, Thabit MN, Koganemaru S, Fukuyama H, Kawamata T
    • Organizer
      29th International Congress of Clinical Neurophysiology
    • Place of Presentation
      Kobe, Japan
    • Year and Date
      2010-10-01
  • [Presentation] A mirror reflection of a hand revealsinterhemispheric asymmetry in themodulation of the stimulus-induced 20-Hzactivity2010

    • Author(s)
      Tominaga W, Matsubayashi J, Nakamura M, Minami C, Kinai T, Matsubayashi M, Mima T, Fukuyama H, Mitani A
    • Organizer
      29th International Congress of Clinical Neurophysiology
    • Place of Presentation
      Kobe, Japan
    • Year and Date
      2010-10-01
  • [Presentation] Different dopaminergic modulation tomotor cortical plasticity in Parkinson' sdisease and multiple system atrophy2010

    • Author(s)
      Ueki Y, Mima T, Kawashima S, Matsukawa N, Fukuyama H, Ojika K
    • Organizer
      29th International Congress of Clinical Neurophysiology
    • Place of Presentation
      Kobe, Japan
    • Year and Date
      2010-10-01
  • [Presentation] 手の鏡像による感覚運動皮質興奮性の半球間非対称性-脳磁図を用いた検討2010

    • Author(s)
      冨永渉、松林潤、木内隆裕、南千尋、中村めぐみ、松橋眞生、美馬達哉、福山秀直、三谷章
    • Organizer
      Neuro2010
    • Place of Presentation
      神戸
    • Year and Date
      2010-09-01
  • [Presentation] 報酬信号によるヒト一次運動野活動の変化2010

    • Author(s)
      美馬達哉、Mohamed Thabit、中塚昌博、福山秀直
    • Organizer
      Neuro2010
    • Place of Presentation
      神戸
    • Year and Date
      2010-09-01
  • [Presentation] ヒト非侵襲的脳刺激のフロンティア2010

    • Author(s)
      美馬達哉、内藤栄一
    • Organizer
      Neuro2010
    • Place of Presentation
      神戸
    • Year and Date
      2010-09-01
  • [Presentation] 経頭蓋的磁気刺激によるヒト脳可塑性の誘導とドパミン系2010

    • Author(s)
      美馬達哉
    • Organizer
      第4回Neurorehabilitetion Conference
    • Place of Presentation
      東京
    • Year and Date
      2010-07-01
  • [Presentation] ヒトのてんかん発作症状における脳幹、視床の関与の可視化の検討2010

    • Author(s)
      井内盛遠、加藤竹雄、粟屋智就、松本理器、澤本伸克、今村久司、中川朋一、美馬達哉、高橋良輔、池田昭夫、福山秀直
    • Organizer
      第51回日本神経学会総会
    • Place of Presentation
      東京
    • Year and Date
      2010-05-01
  • [Presentation] 随意運動の意思のタイミングにおけるー次運動の関与-反復経皮的磁気刺激による検討-2009

    • Author(s)
      植木美乃、美馬達哉、福山秀直
    • Organizer
      第32回日本神経科学大会
    • Place of Presentation
      名古屋
    • Year and Date
      20090000
  • [Presentation] 金銭的報酬課題によるヒト脳可遡性の変化-fMRIと磁気刺激の併用法による検討-2009

    • Author(s)
      美馬達哉
    • Organizer
      特定領域研究「統合脳」5領域冬の公開シンポジウム
    • Place of Presentation
      合同領域会議、一ツ橋
    • Year and Date
      2009-12-01
  • [Presentation] ヒト運動野における両側半球対刺激の側方性の検討2009

    • Author(s)
      小金丸聡子、美馬達哉、中塚昌博、植木美乃、福山秀直、道免和久
    • Organizer
      第39回日本臨床神経生理学会学術大会
    • Place of Presentation
      北九州市
    • Year and Date
      2009-11-01
  • [Presentation] 文字の認識に大脳-次運動野が関与している2009

    • Author(s)
      中塚昌博、美馬達哉、福山秀直
    • Organizer
      第39回日本臨床神経生理学会学術大会
    • Place of Presentation
      北九州市
    • Year and Date
      2009-11-01
  • [Presentation] Stop-signal課題における抑制機能:TMSとfMRIを用いて2009

    • Author(s)
      美馬達哉
    • Organizer
      第39回日本臨床神経生理学会学術大会
    • Place of Presentation
      北九州市
    • Year and Date
      2009-11-01
  • [Presentation] Recovery of upper limb function induced byenhanced use-dependent plasticityapplying the high-frequency rTMS inchronic stroke2009

    • Author(s)
      Koganemaru S, Mima T, Sawamoto N, Domen K, Fukuyama H
    • Organizer
      Neuroscience 2009
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2009-10-01
  • [Presentation] Common prefrontal activity duringinhibition of hand and foot responses2009

    • Author(s)
      Tabu H, Mima T, Sawamoto N, Fukuyama H
    • Organizer
      Neuroscience 2009
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2009-10-01
  • [Presentation] 下肢運動イメージ中の20HZ律動脳磁場活動の変動2009

    • Author(s)
      木内隆裕、松林潤、南千尋、長峯隆、松橋眞生、美馬達哉、福山秀直、三谷章
    • Organizer
      第32回日本神経科学大会
    • Place of Presentation
      名古屋
    • Year and Date
      2009-09-01
  • [Presentation] ヒト運動皮質の神経機構における情動の影響2009

    • Author(s)
      小金丸聡子、美馬達哉、福山秀直、道免和久
    • Organizer
      第32回日本神経科学大会
    • Place of Presentation
      名古屋
    • Year and Date
      2009-09-01
  • [Presentation] 運動制御における前頭前野の体部位局在性の検討2009

    • Author(s)
      椨勇人、美馬達哉、麻生俊彦、福山秀直、高橋良輔
    • Organizer
      第32回日本神経科学大会
    • Place of Presentation
      名古屋
    • Year and Date
      2009-09-01
  • [Presentation] 手の鏡像による20HZ律動脳磁場活動の変化2009

    • Author(s)
      富永渉、松林潤、中村めぐみ、長峯隆、松橋眞生、美馬達哉、福山秀直、三谷章
    • Organizer
      第32回日本神経科学大会
    • Place of Presentation
      名古屋
    • Year and Date
      2009-09-01
  • [Presentation] 文字の認識におけるー次運動の関与-TMSによる検討2009

    • Author(s)
      中塚昌博、美馬達哉、福山秀直
    • Organizer
      第32回日本神経科学大会
    • Place of Presentation
      名古屋
    • Year and Date
      2009-09-01
  • [Presentation] 運動を観察しながら行う運動イメージ:脳波を用いた研究2009

    • Author(s)
      松林潤、松橋眞生、富永渉、中村めぐみ、美馬達哉、福山秀直、三谷章
    • Organizer
      第32回日本神経科学大会
    • Place of Presentation
      名古屋
    • Year and Date
      2009-09-01
  • [Presentation] 視空間ワーキングメモリ課題遂行中の脳磁場活動2009

    • Author(s)
      南千尋、松林潤、木内隆裕、長峯隆、松橋眞生、美馬達哉、福山秀直、三谷章
    • Organizer
      第32回日本神経科学大会
    • Place of Presentation
      名古屋市
    • Year and Date
      2009-09-01
  • [Presentation] Movement-related associative stimulationcan induce human motor cortical plasticity2009

    • Author(s)
      Mohamed Thabit、植木美乃、小金丸聡子、福山秀直、美馬達哉
    • Organizer
      第32回日本神経科学大会
    • Place of Presentation
      名古屋
    • Year and Date
      2009-09-01
  • [Presentation] Involvement of human motor cortex in therecognition of hand-written or blockletters-A TMS study2009

    • Author(s)
      Nakatsuka M, Mima T, Fukuyama H
    • Organizer
      Movement Disorder Society 13th International Congress
    • Place of Presentation
      Paris, France
    • Year and Date
      2009-06-01
  • [Remarks] ホームページ

    • URL

      http://hbrc.kuhp.kyoto-u.ac.jp/

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Published: 2013-07-31  

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