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2011 Fiscal Year Final Research Report

Understanding of multicellular

Research Project

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Project/Area Number 21740077
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field General mathematics (including Probability theory/Statistical mathematics)
Research InstitutionKyushu University

Principal Investigator

YOSHIDA Hiroshi  九州大学, 数理学研究院, 准教授 (60401262)

Project Period (FY) 2009 – 2011
Keywords数理モデル / フィボナッチ数 / 楕円曲線
Research Abstract

I constructed a stochastic model of a cell chain over a Lindenmayer system. Using symbolic computation, I derived explicit relations between cell-type diversity and cell-type ratio constraint. These relations were described as elliptic curveand Fibonacci number-related equations. I further modeled a cell chain with Dachsous : Fat heterodimers and analyzed it. I parameterized redistribution of the heterodimers during cell division. Using prime ideal decomposition, I derived equations in parameters to regenerate the heterodimeric pattern even if part of the cell chain is excised. I thus obtained a regeneration and type-diversity condition necessary for multicells.

  • Research Products

    (9 results)

All 2012 2011 2010 2009

All Journal Article (3 results) (of which Peer Reviewed: 2 results) Presentation (6 results)

  • [Journal Article] "A condition for regeneration of a cell chain inspired by the Dachsous-Fat system,"2011

    • Author(s)
      Hiroshi Yoshida
    • Journal Title

      Journal of Math-for-Industry

      Volume: 3 Pages: 93-98

    • Peer Reviewed
  • [Journal Article] Hiroshi Yoshida, Yoshihiro Miwa and Masanobu Kaneko,"Elliptic curves and Fibonacci numbers arising from Lindenmayer system with Symbolic Computation,"2011

    • Author(s)
      Hiroshi Yoshida
    • Journal Title

      Applicable Algebra in Engineering, Communication and Computing

      Volume: 22 Pages: 147-164

    • Peer Reviewed
  • [Journal Article] 金子昌信『リンデンマイヤシステム上の多細胞モデルにおける楕円曲線を含む曲線』2009

    • Author(s)
      吉田寛
    • Journal Title

      第5回「生物数学の理論とその応用」

      Volume: 1663 Pages: 14-19

  • [Presentation] Tetsuya Bando, and Sumihare Noji"A model of cell-division stop for the limbregeneration,"2012

    • Author(s)
      Hiroshi Yoshida
    • Organizer
      BSCB/BSDB/JSDB Joint meeting
    • Place of Presentation
      Univ. of Warwick
    • Year and Date
      20120415-18
  • [Presentation] Tetsuya Bando, and Sumihare Noji"A Model for Cell-divisionStop and Regeneration based on Dachsous/Fat heterodimer system,"2012

    • Author(s)
      Hiroshi Yoshida
    • Organizer
      The 2nd international conference on the Cricket/RNAi Symposium
    • Place of Presentation
      The University of Tokushima
    • Year and Date
      2012-03-19
  • [Presentation] Tetsuya Bando, and Sumihare Noji"Models of Cell-division Stoppage based onDachsous/Fat heterodimer system,"2011

    • Author(s)
      Hiroshi Yoshida
    • Organizer
      the 21st CDB Meeting"from Regeneration Biology to Regenerative Medicine"
    • Place of Presentation
      RIKEN CDB, Kobe
    • Year and Date
      20111224-26
  • [Presentation] 『Regenerative equations of Dachsous=Fat heterodimeric system』2011

    • Author(s)
      吉田寛
    • Organizer
      第4 9回生物物理学会
    • Place of Presentation
      姫路
    • Year and Date
      2011-09-17
  • [Presentation] "A condition for regeneration of a cell chain based on Dachsous : Fat heterodimer system,"2011

    • Author(s)
      Hiroshi Yoshida
    • Organizer
      The European Conference on Mathematical and Theoretical Biology. ECMTB 2011-
    • Place of Presentation
      Krakow, Poland
    • Year and Date
      2011-06-30
  • [Presentation] 『Cleavage Automata for the egg cleavage and the cockroach leg regeneration』2010

    • Author(s)
      吉田寛
    • Organizer
      生物物理学会
    • Place of Presentation
      仙台
    • Year and Date
      20100900

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Published: 2013-07-31  

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