2010 Fiscal Year Final Research Report
Analysis of bacteriophage Qβ genome evolution in an experimental coevolution system
Project/Area Number |
21770255
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
Evolutionary biology
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Research Institution | Hirosaki University |
Principal Investigator |
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Project Period (FY) |
2009 – 2010
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Keywords | 共進化 / 実験進化 / Qβファージ / 大腸菌 |
Research Abstract |
How does evolution affect changes in parasite genome sequences? To elucidate the effects of coevolution, we constructed an experimental coevolution system and sole parasite evolution system consisting of Escherichia coli and the lytic RNA bacteriophage Qβ (Qβ phage). We passaged Qβ phage in both systems for approximately 170 phage generations. Comparison of sequential (time-dependent) changes in the Qβ phage genome sequence in both evolution systems revealed that the coevolution system showed about 3.4-fold higher fixation rate.
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[Journal Article] PLoS ONE2011
Author(s)
Kazufumi Hosoda, Shingo Suzuki, Yoshinori Yamauchi, Yasunori Shiroguchi, Akiko Kashiwagi, Naoaki Ono, Kotaro Mori, Tetsuya Yomo
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Journal Title
issue 2
Volume: volume 6
Pages: e17105
Peer Reviewed
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[Journal Article]2011
Author(s)
Kumiko Kihara, Kotaro Mori, Shingo Suzuki, Kazufumi Hosoda, Akito Yamada, Shin'ichi Matsuyama, Akiko Kashiwagi, Tetsuya Yomo
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Journal Title
Bio Systems
Volume: vol.13
Pages: 342-347
Peer Reviewed
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[Journal Article]2010
Author(s)
Toshihiko Kishimoto, Leo Iijima, Makoto Tatsumi, Naoaki Ono, Ayana Oyake, Tomomi Hashimoto, Moe Matsuo, Masato Okubo, Shingo Suzuki, Kotaro Mori, Akiko Kashiwagi, Chikara Furusawa, Bei-Wen Ying, Tetsuya Yomo
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Journal Title
PLoS Genetics
Volume: vol.6(10)
Pages: e1001164
Peer Reviewed
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[Journal Article]2009
Author(s)
Saburo Tsuru, Junya Ichinose, Akiko Kashiwagi, Bei-Wen Ying, Kunihiko Kaneko, Tetsuya Yomo
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Journal Title
Physical Biology
Volume: vol.6
Pages: 036015(9pp)
Peer Reviewed
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[Presentation] APBioChEC’092009
Author(s)
Akiko Kashiwagi, Takahiro Sakurai, Saburo Tsuru, Bei-Wen Ying, Kotaro Mori, Tetsuya Yomo
Place of Presentation
Kobe, JAPAN
Year and Date
20091124-28
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