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2013 Fiscal Year Final Research Report

Development of the ISVSr(irregular shaking and vibration stimulator) which is new physical therapy, and study of the content effective for the prevention of bone fracture by using it.

Research Project

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Project/Area Number 22500484
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Rehabilitation science/Welfare engineering
Research InstitutionFujita Health University

Principal Investigator

YAMADA Kouji  藤田保健衛生大学, 医療科学部, 准教授 (60278306)

Project Period (FY) 2010-04-01 – 2014-03-31
Keywords骨密度低下 / 骨折予防 / ISVSr / 筋肥大 / 体脂肪
Research Abstract

The osteoporosis has a massive impact primarily on trabecular bone as a result of the postmenopausal decline in estrogen. The current study used a model of the decrease in bone density in ovariectomized mice to simulate postmenopausal women. Physical therapy to prevent a decrease in bone density was studied via stimulus in the form of rotation of a platform. Analysis of bone histomorphometry revealed lessening of the decrease in bone density of the lumbar vertebrae, a feat that the stimulus from conventional physical therapy had failed to achieve.
With muscles that function as two-joint muscles such as the psoas major, differences exist in muscular hypertrophy, generation and differentiation between origin and insertion sides.

  • Research Products

    (12 results)

All 2013 2012 2011 2010

All Journal Article (4 results) (of which Peer Reviewed: 4 results) Presentation (8 results)

  • [Journal Article] Stimulus in the form of rotation and shaking of a platform and its effect on the formation of trabecular bone in the lumbar vertebrae of mice2013

    • Author(s)
      Yamada K, Nishii K, Sakai K, Teranishi T
    • Journal Title

      Aging Clin Exp Res

      Volume: 25(6) Pages: 625-32

    • Peer Reviewed
  • [Journal Article] Shaking stimuli can retard accelerated decline of bone strength of a mouse model assumed to represent a postmenopausal woman2010

    • Author(s)
      Yamada K, Nishii K, Hida T
    • Journal Title

      J Anal Bio-Sci

      Volume: 33(4) Pages: 355-36

    • Peer Reviewed
  • [Journal Article] Shaking stimuli may prevent bone fracture by restraining a bone density decrease gently2010

    • Author(s)
      Yamada K, Nishii K, Sawada H, Ito M, Aizu N, Dohi S Hida T
    • Journal Title

      J Anal Bio-Sci

      Volume: 33(2) Pages: 141-150

    • Peer Reviewed
  • [Journal Article] 振盪刺激がマウス大腰筋に及ぼす影響について2010

    • Author(s)
      伊藤正典, 西井一宏, 会津直樹, 土肥さやか, 肥田岳彦, 山田晃司
    • Journal Title

      組織学と特異的タンパク質の発現量からの検討形態・機能

      Volume: 第9巻, 1号 Pages: 3-11

    • Peer Reviewed
  • [Presentation] Stimulus in the form of rotation and shaking of a platform and its effect on the formation of trabecular bone in the lumbar vertebrae of mice2013

    • Author(s)
      山田晃司, 西井一宏, 酒井一由, 寺西利生
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      神戸
    • Year and Date
      20131203-06
  • [Presentation] インナーマッスルを鍛える運動療法により骨強度を保たせる刺激方法の検討2012

    • Author(s)
      山田晃司, 西井一宏, 酒井一由, 寺西利生, 肥田岳彦
    • Organizer
      第85回日本生化学大会
    • Place of Presentation
      福岡
    • Year and Date
      20121214-16
  • [Presentation] 老化に伴う骨密度低下が原因の腰椎圧迫骨折を予防する刺激方法の検討2012

    • Author(s)
      山田晃司, 西井一宏, 酒井一由, 澤田浩秀, 肥田岳彦
    • Organizer
      第117回日本解剖学会総会
    • Place of Presentation
      甲府
    • Year and Date
      20120326-28
  • [Presentation] 老化に伴う骨密度低下を緩和する刺激装置の開発と検討コ・メディカル形態機能学会2012

    • Author(s)
      山田晃司, 西井一宏, 酒井一由, 肥田岳彦
    • Organizer
      第11回学術集会
    • Place of Presentation
      東京
    • Year and Date
      2012-09-22
  • [Presentation] 老化に伴う腰椎の圧迫骨折を予防する運動療法の開発2011

    • Author(s)
      山田晃司, 西井一宏, 澤田浩秀, 肥田岳彦
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      20111213-16
  • [Presentation] 閉経後女性を想定した老化に伴う骨折を予防するための運動療法の開発2011

    • Author(s)
      山田晃司, 西井一宏, 肥田岳彦
    • Organizer
      第84回日本生化学大会
    • Place of Presentation
      京都
    • Year and Date
      20110921-24
  • [Presentation] 震盪刺激装置を用いた運動療法がマウス下肢帯の筋に与える影響について2010

    • Author(s)
      山田晃司, 伊藤正典, 西井一宏, 肥田岳彦
    • Organizer
      第33回日本分子生物学会年会第83回日本生化学大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      20101207-10
  • [Presentation] 水平板回転装置による刺激がマウス下肢筋に与える効果の分析2010

    • Author(s)
      山田晃司, 伊藤正典, 西井一宏, 会津直樹, 土肥さやか, 名和史朗, 大川麻樹, 肥田岳彦
    • Organizer
      第115回日本解剖学会総会
    • Place of Presentation
      盛岡
    • Year and Date
      20100328-30

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Published: 2015-07-16  

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