2012 Fiscal Year Final Research Report
Effects of Soy Yogurt on Lowering Inflammatory Cytokine
| Project/Area Number |
22500788
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Eating habits, studies on eating habits
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| Research Institution | Mukogawa Women's University |
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Principal Investigator |
FUKUDA Mitsuru 武庫川女子大学, 生活環境学部, 教授 (90098517)
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| Co-Investigator(Kenkyū-buntansha) |
KOBAYASHI Maki (田中 麻貴) 武庫川女子大学, 生活環境学部, 助手 (70550789)
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| Project Period (FY) |
2010 – 2012
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| Keywords | TNF一α / アグリコン / イソフラボン / ラット / 乳酸発酵 / 大豆 / 炎症性サイトカ |
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| Research Abstract |
In plasma of rats fed a high fat and high cholesterol diet, isofavone level was increased and TNF-a level was decreased by ingestion of soy yogurt. The increase of visceral fat mass was suppressed and the gene expression of TNF-a in visceral fat tissue was down-regulated by ingestion of soy yogurt. It was assumed that the visceral fat mass in rats was decreased by ingestion of soy yogurt and thereby the level of plasma inflammatory cytokine was mainly reduced through modulation of gene expression in visceral fat tissue.
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