2011 Fiscal Year Final Research Report
The effect of running on the expression of microRNA in rats
| Project/Area Number |
22700595
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Physical education
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| Research Institution | Matsusho Gakuen Junior College |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2011
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| Keywords | 運動 / 海馬 / 神経新生 / microRNA |
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| Research Abstract |
Voluntary exercise has been reported to promote neurogenesis in the hippocampus and to improve learning and memory, the function of hippocampus. However, the mechanisms is yet unknown. Recently, it is suggested that short forms of RNA, microRNA(miRNA), may be involved in the neuronal differentiation and neurogenesis. In the present study, the expression level of miRNAs in the hippocampus was investigated after 12 days of voluntary running exercise in the mouse. As the result, no significant change was detected in the hippocampal miRNAs investigated. There may be a possibility that the expression of miRNAs would be changed in the early phase of voluntary exercise or acute exercise.
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