2016 Fiscal Year Final Research Report
A study on brain mechanism and new treatment strategy of substance and non-substance addiction
| Project/Area Number |
23591682
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Psychiatric science
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| Research Institution | Jikei University School of Medicine |
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Principal Investigator |
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| Research Collaborator |
Murona Naoya
Yoshida Takuma
Ota Junpei
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| Project Period (FY) |
2011-04-28 – 2017-03-31
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| Keywords | 依存 / 嗜癖 / 物質 / 行動 / 欲求 / 一次性強化効果 / 二次性強化効果 / 離脱症状 |
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| Outline of Final Research Achievements |
The purpose of the present study is to investigate whether or not substance addiction and behavioral addiction are categorized into the same psychiatric disease. For that purpose, the structure of craving was hypothetically divided into three components, i.e., the primary reinforcing effects, negative affective symptoms during withdrawal, and the secondary conditioning effects of environmental stimulus. Then, the characteristics of substance addiction and behavioral addiction was compared from the perspective of the structure of craving. Both types of addiction showed the similarity in the negative affective symptoms during withdrawal, the secondary conditioning effects of environmental stimulus, and impulsivity accompanied with addiction. However, both types of addiction differed in that the primary reinforcing effects of behavioral addiction was greatly affected by a biological state of a subject, whereas those of substance addiction were not.
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| Free Research Field |
精神医学
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