2012 Fiscal Year Final Research Report
Screening of anti-virus activities from deep-sea-adapted bacteria
Project/Area Number |
23780198
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Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
General fisheries
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Research Institution | Osaka University of Pharmaceutical Sciences (2012) Nagasaki University (2011) |
Principal Investigator |
KAWANO Hiroaki 大阪薬科大学, 薬学部, ポストドクター (60409133)
|
Project Period (FY) |
2011 – 2012
|
Keywords | 微生物 / 深海 |
Research Abstract |
We isolated deep-sea-adapted bacteria from deep-sea-mud samples collected at the Japan sea, Sagami bay, and Japan trench. These bacteria were stored as a bacterial library and their diversity was analyzed based on the 16S rDNA nucleotide sequences. One thousand bacteria were cultured and the resulting supernatants were stored so as to be used for anti-virus activity screening. In addition, establishment of EGFP/NLS/NES cell line which will be used for anti-virus activity screening was successfully achieved. Furthermore, we found significant anti-influenza virus activities in13 supernatant mixtures of deep-sea bacterial cultures.
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Research Products
(1 results)