• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to project page

Products Report

VCP阻害剤による眼疾患に対する新たな神経保護治療法の研究開発

Research Project

Project/Area Number 24249082
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Research Field Ophthalmology
Research InstitutionKyoto University

Principal Investigator

YOSHIMURA Nagahisa  京都大学, 医学(系)研究科(研究院), 教授 (70211662)

Co-Investigator(Kenkyū-buntansha) IKEDA Ohashi Hanako  京都大学, 医学部附属病院, 准教授 (20372162)
KAKIZUKA Akira  京都大学, 大学院生命科学研究科, 教授 (80204329)
IMAMURA Hiromi  京都大学, 白眉センター, 特定准教授 (20422545)
Project Period (FY) 2012-10-31 – 2015-03-31
  • Research Products

    (9 results)

All 2018 2017 2016 2015 2014 2011

All Journal Article (6 results) (of which Open Access: 6 results) Patent(Industrial Property Rights) (3 results) (of which Overseas: 1 results)

  • [Journal Article] KUS121, an ATP regulator, mitigates chorioretinal pathologies in animalmodels of age-related macular degeneration.2018

    • Author(s)
      Muraoka, Y., Yoshimura, N., et al.
    • Journal Title

      Heliyon

      Volume: 4 Pages: e00624

    • DOI

      10.1016/j.heliyon.2018.e00624

    • Open Access
  • [Journal Article] Modulation of valosin-containing protein by Kyoto University Substances (KUS) as a novel therapeutic strategy for ischemic neuronal diseases.2017

    • Author(s)
      Hata, M. & Ikeda, H. O.
    • Journal Title

      Neural regeneration research

      Volume: 12 Pages: 1252-1255

    • DOI

      10.4103/1673-5374.213540

    • Open Access
  • [Journal Article] KUS121, a VCP modulator, attenuates ischemic retinal cell death viasuppressing endoplasmic reticulum stress.2017

    • Author(s)
      Hata, M., Yoshimura, N., et al.
    • Journal Title

      Scientific reports

      Volume: 7 Pages: 44873

    • DOI

      10.1038/srep44873

    • Open Access
  • [Journal Article] Changes in morphology and visual function over time in mouse models of retinal degeneration : an SD-OCT, histology, and electroretinography study.2016

    • Author(s)
      Hasegawa, T., Yoshimura, N., et al.
    • Journal Title

      Japanese journal of ophthalmology

      Volume: 60 Pages: 111-125

    • DOI

      10.1007/s10384-015-0422-0

    • Open Access
  • [Journal Article] Neurprotective efficacies by KUS121, a VCP modulator, on animal models of retinal degeneration.2016

    • Author(s)
      Hasegawa, T. Yoshimura, N., et al.
    • Journal Title

      Scientific reports

      Volume: 6 Pages: 31184

    • DOI

      10.1038/srep31184

    • Open Access
  • [Journal Article] Neuroprotective effects of VCP modulators in mouse models of glaucoma.2016

    • Author(s)
      Nakano, N., Yoshimura, N., et al.
    • Journal Title

      Heliyon

      Volume: 2 Pages: 96

    • DOI

      10.1016/j.heliyon.2016.e00096

    • Open Access
  • [Patent(Industrial Property Rights)] 虚血性眼疾患の処置および/または予防用の医薬組成物2015

    • Inventor(s)
      垣塚彰、池田華子、吉村長久, 他1名
    • Industrial Property Rights Holder
      国立大学法人京都大学
    • Industrial Property Number
      PCT/JP2015/055619
    • Filing Date
      2015-02-26
    • Overseas
  • [Patent(Industrial Property Rights)] 眼疾患処置薬2014

    • Inventor(s)
      垣塚彰、池田華子、吉村長久, 他1名
    • Industrial Property Rights Holder
      国立大学法人京都大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      14754749
    • Filing Date
      2014-02-19
    • Acquisition Date
      2017-12-22
  • [Patent(Industrial Property Rights)] 眼疾患処置薬2011

    • Inventor(s)
      垣塚彰、堀清次、池田華子、吉村長久, 他3名
    • Industrial Property Rights Holder
      国立大学法人京都大学、他一社
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      5822840
    • Filing Date
      2011-09-30
    • Acquisition Date
      2015-10-16

URL: 

Published: 2019-02-27  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi