2015 Fiscal Year Final Research Report
Serological and molecular epidemiological studies on Asian zoonotic schistosomiasis in the Philippines
| Project/Area Number |
24405044
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 海外学術 |
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| Research Field |
Applied veterinary science
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| Research Institution | Obihiro University of Agriculture and Veterinary Medicine |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KIRINOKI Masashi 獨協医科大学, 医学部, 准教授 (50265302)
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| Co-Investigator(Renkei-kenkyūsha) |
KADOHIRA Mutsuyo 帯広畜産大学, 畜産学部, 教授 (20313976)
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| Project Period (FY) |
2012-04-01 – 2016-03-31
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| Keywords | 人獣共通感染症 / 日本住血吸虫症 / フィリピン / 保虫宿主 / 中間宿主貝 |
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| Outline of Final Research Achievements |
Serological and molecular epidemiological studies for the reservoir host animals on Asian zoonotic schistosomiasis were conducted in the Philippines. In addition, preliminary analysis on genetic diversity of Schistosoma japonicum in the study sites using microsatellite markers was also done. (1) The field study suggested that water buffaloes and dogs are the major animal reservoirs contributing to human transmission of S. japonicum in Central Visayas and Southern Mindanao regions in the Philippines. (2) The study also indicated the importance of utilizing water buffaloes as sentinel animals for schistosomiasis surveillance. (3) The analytical protocol for multi-locus genotyping (MLG) was established using 10 microsatellite markers. (4) Preliminary analysis among parasite populations from 4 study sites revealed that there are no particular spatial structuring among these parasite populations. This finding suggested that there is an on-going gene flow between the populations.
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| Free Research Field |
獣医学
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