2015 Fiscal Year Final Research Report
The research for Mg availability and dynamics during exercise
| Project/Area Number |
24500797
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Sports science
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| Research Institution | Josai International University |
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Principal Investigator |
SAKAI Kensuke 城西国際大学, 薬学部, 准教授 (70406784)
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| Project Period (FY) |
2012-04-01 – 2016-03-31
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| Keywords | 運動 / マグネシウム / TRPM7 |
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| Outline of Final Research Achievements |
Exercise loading induced the increase in apparent Mg absorption and the expression of TRPM7, which is one of Mg-transporter in rat skeletal muscle. Especially in immediately after exercise, the expression of TRPM7 was elevated, it will be suggested that exercise-induced metabolic acidosis related to the expression of TRPM7. The expression pattern of TRPM7 in metabolic acidosis rat induced administrated 1.5% NH4Cl solution was different from in swimming exercised rat. Moreover other Mg-transporters, such as TRPM6 and CLDN16 were expressed in kidney and intestine. These results suggested that some Mg-transporters affect Mg dynamics in exercised rat.
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| Free Research Field |
スポーツ栄養学
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