Structural study of florigen and the receptor complex

2014 Fiscal Year Final Research Report

• Project/Area Number: 24570133
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Structural biochemistry
• Research Institution: Kyoto University (2014); Nara Institute of Science and Technology (2012-2013)
• Principal Investigator: OHKI Izuru 京都大学, 工学(系)研究科(研究院), 研究員 (80418574)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: X線結晶解析 / NMR / 植物 / 植物ホルモン / 構造生物学 / 花成

Outline of Final Research Achievements

Florigen is a mobile plant hormone that determines the flowering time in higher plants, but its regulatory mechanism remains unclear. In this study, we focused on an anti-florigen, which suppresses flowering antagonizing with florigen, to clarify the role in floral regulation. From structural and biochemical analysis, anti-florigen was found to form a stable complex with florigen receptor and inhibit formation of florigen-receptor complex. The bindings of florigen and anti-florigen to receptor were exchangeable, suggesting that the balance of the two proteins is important for determining floral transition.

Free Research Field

構造生物学