Fundamental study on the modulation mechanism of orofacial pain by the taste and olfactory sensations and its application to clinical use.

2014 Fiscal Year Final Research Report

• Project/Area Number: 24593053
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Surgical dentistry
• Research Institution: Niigata University
• Principal Investigator: TANAKA Yutaka 新潟大学, 医歯学総合病院, 講師 (50323978)
• Co-Investigator(Kenkyū-buntansha): SEO Kenji 新潟大学, 医歯学系, 教授 (40242440) ; TERUMITSU Makoto 新潟大学, 医歯学系, 准教授 (60401767) ; YAMAMURA Kensuke 新潟大学, 医歯学系, 教授 (90272822) ; KURATA Shigenobu 新潟大学, 医歯学系, 助教 (20464018) ; YOSHIKAWA Hiroyuki 新潟大学, 医歯学総合病院, 医員 (20547575)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: 口腔顔面痛 / 慢性疼痛 / 味覚刺激 / 嗅覚刺激 / 疼痛変調機構 / 歯科心身症

Outline of Final Research Achievements

The aim of this study was to examine the possibility of reduction of orofacial pain and to investigate the modulation mechanism of orofacial pain by the taste and olfactory stimulation.The subjects of this study were patients with chronic orofacial pain that treaded in our department.All the subjects underwent gustatory test and olfactometric tests,and were evaluated with self-answerd type pain score(VAS), various psychological tests, autonomic activity analysis, and near-infrared spectroscopy.As a result, in all the subjects, orofacial pain intensity didn’t change by olfactory test. On the other hand, gustatory test by sweet taste decreased pain intensity（VAS）transient in the glossalgia patients.This study suggest that the sweet taste stimulation may have a transient pain reduction mechanism of glossalgia among orofacial pain.

Free Research Field

歯科麻酔学