Sex differences in the control of cerebral blood flow during exercise

2016 Fiscal Year Final Research Report

• Project/Area Number: 25282184
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Partial Multi-year Fund
• Section: 一般
• Research Field: Developmental mechanisms and the body works
• Research Institution: Japan Women's College of Physical Education
• Principal Investigator: Sadamoto Tomoko 日本女子体育大学, 体育学部, 教授 (30201528)
• Co-Investigator(Kenkyū-buntansha): 小河 繁彦 東洋大学, 理工学部, 教授 (80553841)
• Co-Investigator(Renkei-kenkyūsha): NATSUI HIROAKI 日本女子体育大学, 体育学部, 教授 (80266858) ; SATO KOHEI 日本女子体育大学, 体育学部, 准教授 (00409278) ; OOUE ANNA 東洋大学, 食環境科学部, 講師 (00550104)
• Research Collaborator: Otsuki Aki 日本女子体育大学, 附属基礎体力研究所, 助教 ; YNEYA MARINA 日本女子体育大学, 附属基礎体力研究所, 技術職員
• Project Period (FY): 2013-04-01 – 2017-03-31
• Keywords: 月経周期 / エストロゲン / プロゲステロン / 内頸動脈 / 椎骨動脈 / 二酸化炭素反応性 / 超音波法

Outline of Final Research Achievements

Circulating estrogen is believed to a dilator of cerebral vessels, but impact of female hormones on the cerebrovascular regulation is not fully understood. In young healthy females, the cerebrovascular CO2 reactivity, a potent mediator of cerebral flow regulation during exercise, was measured in the internal carotid artery (ICA) and the vertebral artery (VA) during early follicular, late follicular, and mid luteal phases of menstrual cycle. The CO2 reactivity in females was similar to that observed in males and unchanged across three phases of menstrual cycle in both ICA and VA, suggesting that female hormones are not determining factors for the cerebrovascular CO2 reactivity.

Free Research Field

運動生理学