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2015 Fiscal Year Final Research Report

Development and evaluation of tricalcium phosphate-based ceramic material having osteogenesis promoting action

Research Project

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Project/Area Number 25350554
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Biomedical engineering/Biomaterial science and engineering
Research InstitutionChiba Institute of Technology

Principal Investigator

HASHIMOTO Kazuaki  千葉工業大学, 工学部, 教授 (90255159)

Project Period (FY) 2013-04-01 – 2016-03-31
Keywordsバイオセラミックス / リン酸三カルシウム / 生体吸収性材料 / 置換固溶体
Outline of Final Research Achievements

In this study, Ca site (cation site) in β type tricalcium phosphate (β-TCP) was substituted to monovalent, divalent or trivalent metal ions using a living body essential element and P site (anion site) was simultaneously substituted to various oxyacid salt ions. The obtained substituted solid solution was established the manufacturing method of the sintering body. In addition, the obtained sintering bodies were evaluated for solubility using various solution, for the interaction with the osteoblasts and the osteoclast cell.

Free Research Field

バイオセラミックス

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Published: 2017-05-10  

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