2014 Fiscal Year Final Research Report
| Project/Area Number |
25893227
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Pediatrics
|
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| Research Institution | Saitama Medical University |
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Principal Investigator |
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| Project Period (FY) |
2013-08-30 – 2015-03-31
|
| Keywords | 成人先天性心疾患 / 心血管機能 / フォンタン循環 / 交感神経 / 静脈キャパシタンス / 心不全 / 運動耐用能 |
|---|
| Outline of Final Research Achievements |
We studied the mechanism leading to pathogenesis to establish the appropriate treatment and management of adult congenital heart disease(ACHD) from the point of the cardiovascular function. In patients after Fontan surgery for functional single ventricle, the importance of abnormal sympathetic activation was suggested as well as heart failure patients. Sympathetic activation decreases venous capacitance (Cv). Reduced Cv may be associated with the midterm outcomes and complications after Fontan surgery. Waon therapy was useful as intervention for Cv. We also studied the right heart failure of congenitally corrected transposition and tetralogy of Fallot as other type of ACHD.
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| Free Research Field |
小児循環器学
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