Approach to molecular system controlling left-right asymmetry of flatfish body color using next generation techniques

2016 Fiscal Year Final Research Report

• Project/Area Number: 26292110
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Partial Multi-year Fund
• Section: 一般
• Research Field: Aquatic life science
• Research Institution: Tohoku University
• Principal Investigator: SUZUKI Tohru 東北大学, (連合)農学研究科(研究院), 教授 (70344330)
• Co-Investigator(Kenkyū-buntansha): 酒井 義文 東北大学, (連合)農学研究科(研究院), 准教授 (10277361) ; 横井 勇人 東北大学, (連合)農学研究科(研究院), 助教 (40569729)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: 異体類 / 左右非対称 / 発生 / 色素胞分化 / レチノイン酸 / RNA-Seq

Outline of Final Research Achievements

Flounder larvae are externally symmetric commonly to general fishes, but they transform to left-right (L-R) asymmetric body by migrating one eye to the other side of body and then differentiating chromatophores at ocular side skin. In the hatcheries for aquaculture, since abnormal pigmentation, including pigmentation of ocular side and pseudo-albinism of blind side, often appears, elucidation of the mechanism to induce abnormal pigmentation is required. This research revealed cellular and molecular systems that control L-R asymmetric skin color development in flounder, and also abnormal pigmentation

Free Research Field

水産学