| Budget Amount *help |
¥145,340,000 (Direct Cost: ¥111,800,000、Indirect Cost: ¥33,540,000)
Fiscal Year 2021: ¥22,880,000 (Direct Cost: ¥17,600,000、Indirect Cost: ¥5,280,000)
Fiscal Year 2020: ¥24,830,000 (Direct Cost: ¥19,100,000、Indirect Cost: ¥5,730,000)
Fiscal Year 2019: ¥26,520,000 (Direct Cost: ¥20,400,000、Indirect Cost: ¥6,120,000)
Fiscal Year 2018: ¥29,380,000 (Direct Cost: ¥22,600,000、Indirect Cost: ¥6,780,000)
Fiscal Year 2017: ¥41,730,000 (Direct Cost: ¥32,100,000、Indirect Cost: ¥9,630,000)
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| Outline of Final Research Achievements |
This project examined whether fluctuations in the developmental process of chordates contribute to evolutionary conservation (constraints and directions). The results of the study suggested that the developmental stage in which the basic structure of vertebrates is constructed is developmentally stable, showing small fluctuations in gene expression profiles. In addition, we found that this may be one of the contributing factors to the evolutionary conservation of this developmental phase. The experimental data also showed that body plan developing stage is enriched with repeatedly used genes, and this could have contributed to the evolutionary conservation of the body plan developing phase. This also suggests that while gene co-option frequently took place to facilitate the acquisition of new traits, it may also work as a factor that limits phenotypic diversification.
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