Development of a novel type of carbohydrate probes
| Project/Area Number |
15K12760
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Chemical biology
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| Research Institution | Kyushu University (2016-2017)
Institute of Physical and Chemical Research (2015) |
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Principal Investigator |
Hirai Go 九州大学, 薬学研究院, 教授 (50359551)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Keywords | 複合糖質 / シアリダーゼ / 酵素反応 / 分子プローブ / シアル酸 / 代謝 / 有機合成 / プローブ / 有機化学 / 糖鎖 / 生体分子 |
|---|
| Outline of Final Research Achievements |
Carbohydrates (glycoconjugates) have important functions. Degradation of carbohydrates that play a role of "turning off" functions of original carbohydrates, is also important process in cells. However, it is not possible to monitor when or which enzymes degradate a specific glycoconjugate in cells. This time, a new molecular tool that can do this was successfully developed with our own idea.
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Report
(4 results)
Research Products
(27 results)
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[Journal Article] Comparative Characterization of the Leaf Tissue of Physalis alkekengi and Physalis peruviana Using RNA-seq and Metabolite Profiling2016
Author(s)
Atsushi Fukushima, Michimi Nakamura, Hideyuki Suzuki, Mami Yamazaki, Eva Knoch, Tetsuya Mori, Naoyuki Umemoto, Masaki Morita, Go Hirai, Mikiko Sodeoka, and Kazuki Saito
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Journal Title
Frontiers in Plant Science
Volume: 7
Pages: 1883-1883
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
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[Journal Article] Identification of novel secreted fatty acids that regulate nitrogen catabolite repression in fission yeast.2016
Author(s)
Sun X, Hirai G, Ueki M, Hirota H, Wang Q, Hongo Y, Nakamura T, Hitora Y, Takahashi H, Sodeoka M, Osada H, Hamamoto M, Yoshida M, Yashiroda Y.
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Journal Title
Scientific Reports
Volume: 6
Issue: 1
Pages: 20856-20856
DOI
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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