| Budget Amount *help |
¥41,340,000 (Direct Cost: ¥31,800,000、Indirect Cost: ¥9,540,000)
Fiscal Year 2020: ¥7,150,000 (Direct Cost: ¥5,500,000、Indirect Cost: ¥1,650,000)
Fiscal Year 2019: ¥7,540,000 (Direct Cost: ¥5,800,000、Indirect Cost: ¥1,740,000)
Fiscal Year 2018: ¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000)
Fiscal Year 2017: ¥12,090,000 (Direct Cost: ¥9,300,000、Indirect Cost: ¥2,790,000)
Fiscal Year 2016: ¥8,190,000 (Direct Cost: ¥6,300,000、Indirect Cost: ¥1,890,000)
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| Outline of Final Research Achievements |
Chagas disease is a parasitic disease caused by Trypanosoma cruzi transmitted to humans by a Triatomine insects. Chagas disease in Bolivia is endemic that covers half of the country. The National University in Santa Cruz conducts annual antibody testing and the positive rate in 2017 was 5%. The aim of this study was to examine the presence of complications of chronic Chagas disease (cardiac and gastrointestinal diseases) in young people and to identify biomarkers in the blood of those who develop early disease as risk factors and to contribute to early diagnosis. In 2017,72 positive and 53 negative subjects who gave an informed consent were diagnosed for complications by ECG, chest X-ray and contrast-enhanced X-ray of the colon. The results showed, surprisingly, that there was no difference in the frequency of the colonic complication megacolon between the Chagas-positive and negative groups. The same things happened in ECG abnormalities. The results were contrary to expectations.
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