Investigation of human iPS cell derived 3D bone like tissue using hypoxic culture
| Project/Area Number |
16H06643
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Prosthodontics/ Dental materials science and
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| Research Institution | Tohoku University |
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Principal Investigator |
Okawa Hiroko 東北大学, 大学院歯学研究科, 非常勤講師 (00781296)
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| Research Collaborator |
EGUSA Hiroshi 東北大学, 大学院歯学研究科, 教授 (30379078)
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| Project Period (FY) |
2016-08-26 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 再生歯学 / iPS細胞 / 歯学 / 組織工学 / 骨 / 再生医学 |
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| Outline of Final Research Achievements |
Induced pluripotent stem cells (iPS cells) are expected as a stem cell source to be used for regenerative medicine of severe alveolar bone loss. In order to develop iPS cells into clinical application, it is necessary to investigate method of osteogenic differentiation of human iPS cells. In this study, we found that hypoxic culture promotes osteogenic differentiation of iPS cells. It is expected that the results of this research will develop into the establishment of new bone augmentation using iPS cells.
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Report
(3 results)
Research Products
(3 results)
