Study on the development of lncRNA biomarkers in radiation therapy
Project/Area Number |
16K20972
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Tumor diagnostics
Radiation science
|
Research Institution | The University of Tokyo |
Principal Investigator |
Miyagawa Ryu 東京大学, 医学部附属病院, 特任助教 (20721939)
|
Project Period (FY) |
2016-04-01 – 2018-03-31
|
Project Status |
Completed (Fiscal Year 2017)
|
Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2017: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
|
Keywords | がん / 放射線 / 放射線治療 / バイオマーカー / 非コードRNA / 腫瘍診断 / 長塩基長非コードRNA / 癌 / 核酸 / 細胞・組織 |
Outline of Final Research Achievements |
The purpose of this study is to elucidate the new mechanisms of radiation-responsive non-coding RNA (ncRNA) for the establishment of a new biomarker in radiation therapy. I used X-ray-irradiated cancer-derived cultured cells. First, I identified the expressoion change of some ncRNAs by qPCR. Concurrently, I also identified the localization change of some ncRNAs and some proteins by FISH and IF methods. But I was not able to identify the interaction of those ncRNAs with proteins.
|
Report
(3 results)
Research Products
(3 results)