2017 Fiscal Year Final Research Report
Study on the development of lncRNA biomarkers in radiation therapy
Project/Area Number |
16K20972
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Tumor diagnostics
Radiation science
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Research Institution | The University of Tokyo |
Principal Investigator |
Miyagawa Ryu 東京大学, 医学部附属病院, 特任助教 (20721939)
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Project Period (FY) |
2016-04-01 – 2018-03-31
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Keywords | がん / 放射線 / 放射線治療 / バイオマーカー / 非コードRNA |
Outline of Final Research Achievements |
The purpose of this study is to elucidate the new mechanisms of radiation-responsive non-coding RNA (ncRNA) for the establishment of a new biomarker in radiation therapy. I used X-ray-irradiated cancer-derived cultured cells. First, I identified the expressoion change of some ncRNAs by qPCR. Concurrently, I also identified the localization change of some ncRNAs and some proteins by FISH and IF methods. But I was not able to identify the interaction of those ncRNAs with proteins.
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Free Research Field |
分子生物学、細胞生物学、放射線生物学
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