Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2020: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2019: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2018: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
|
Outline of Final Research Achievements |
The aim of this study was to establish an animal model of pancreatic cancer utilizing the pancreas-targeted hydrodynamic gene delivery of human oncogenes in rats. To date, we have successfully developed a novel rat pancreatic cancer model safely and efficiently by optimizing gene delivery parameters, gene concentrations, and gene combinations in order to create efficiently a pancreatic cancer model. Following this development, we are clarifying the molecular mechanism of this pancreatic cancer model to identify the therapeutic target.
|