Budget Amount *help |
¥15,600,000 (Direct Cost: ¥12,000,000、Indirect Cost: ¥3,600,000)
Fiscal Year 2011: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2010: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2009: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2008: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
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Research Abstract |
We identified placenta-specific miRNAs(e. g., miR-517a) that were linked to a miRNA cluster on chromosome 19. Hydroxysteroid(17-beta) dehydrogenese 1(HSD17B1) was dysregulated by miR-210 and miR-518c that were aberrantly expressed in preeclamptic placenta, and reducing plasma level of HSD17B1 preceded the onset of PE. We conclude that plasma HSD17B1 is a potential prognostic factor for PE.
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