Development of New Implant Augmentation Drug Delivery System Using a rh-BMP-2-Gelatin Hydrogel Complex
Project/Area Number |
22791886
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
Prosthetic dentistry
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Research Institution | Hiroshima University |
Principal Investigator |
HAYASHI Kazuhiko 広島大学, 大学院・医歯薬学総合研究科, 助教 (90444687)
|
Project Period (FY) |
2010 – 2011
|
Project Status |
Completed (Fiscal Year 2011)
|
Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2011: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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Keywords | 歯科補綴学一般 / 骨増生 / インプラント / ドラックデリバリーシステム / 成長因子 / rh-BMP-2 / 増生 / ドラッグデリバリーシステム |
Research Abstract |
Optimum dose of rh-BMP-2in gelatin complex was clarified using the bone deficit model of the rabbit parietal bone. The complex was transplanted to the bone deficit model of a hybrid dog. After the observation period, the organization block was extracted, and the specimen was produced and was observed histologically. The bone tissue reproduced inside the bone deficit was observed. When rh-BMP-2quantity became large, the rate of bone area became large.
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Report
(3 results)
Research Products
(3 results)
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[Presentation] Development of Implant/ Interconnected Prorous Calcium Hydroxyapatite Complex2011
Author(s)
Oue, H., Doi, K., Kubo, T., Koretake, K., Hayashi, K., Kajihara, S., Imura, K., Akagawa, Y
Organizer
14th Meeting ofthe International College ofBMP-2 0μgBMP-2 8μgProsthodontists
Place of Presentation
Hawaii, USA
Related Report
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