Induction of differentiation to musculoskeletal tissue with autologous blood-derived scaffold and application to regenerative medicine
| Project/Area Number |
23659722
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Orthopaedic surgery
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| Research Institution | Osaka University |
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Principal Investigator |
KITA Keisuke 大阪大学, 医学系研究科, 特任助教(常勤) (30588869)
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| Co-Investigator(Kenkyū-buntansha) |
NAKATA Ken 大阪大学, 医学系研究科, 講師 (00283747)
MAE Tatsuo 大阪大学, 医学系研究科, 助教 (10569734)
HIGUCHI Chikahisa 大阪大学, 医学系研究科, 助教 (40432421)
NAKAMURA Norimasa 大阪大学, 臨床医工学融合教育センター, 招聘教授 (50273719)
MYOI Akira 大阪大学, 医学部附属病院, 准教授 (10263261)
YOSHIKAWA Hideki 大阪大学, 医学系研究科, 教授 (60191558)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
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| Keywords | 四肢機能再建学 / 自己由来材料 / 半月板再生 / フィブリンクロット / 再生治療 / 膝半月板 / 自己由来スキャフォールド |
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| Research Abstract |
In recent years, usefulness of the technique using artificial materials and animal-derived materials has been reported in the treatment of meniscus which is one of the tissue forming the synovial joint. However, the problems to be overcome, such as infection control and immune response, are still present. The most effective way to solve these problems is to use autologous materials only. Fibrin clot is a tissue with a network structure and is easily created from venous blood. Fibrin clot is highly safe because it is autologous. In this study, we examined the regenerative therapy of meniscus using the fibrin clot.
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Report
(3 results)
Research Products
(12 results)
