| Budget Amount *help |
¥18,590,000 (Direct Cost: ¥14,300,000、Indirect Cost: ¥4,290,000)
Fiscal Year 2014: ¥5,980,000 (Direct Cost: ¥4,600,000、Indirect Cost: ¥1,380,000)
Fiscal Year 2013: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000)
Fiscal Year 2012: ¥6,760,000 (Direct Cost: ¥5,200,000、Indirect Cost: ¥1,560,000)
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| Outline of Final Research Achievements |
Mycoplalasma pneumonia, epidemic recent years is caused by a bacterium, Mycoplasma pneumoniae. Mycoplasmas glide by quite unique mechanisms, which are essential for infection. In this project, we studied the fasest species, Mycoplasma mobile and the pathogenic Mycoplasma pneumoniae and got the following results, (1) namometer-order three dimensional structure of gliding machinery, (2) identification, detecting activity and outline of structure, for essential proteins, (3) ATPase reaction of gliding machinery, (4) behaviors of “leg” molecule, (5) development of gene manipulation method and localization of gliding proteins.
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