Usefulness of FRAX as a screening tool for osteoporosis
Project/Area Number |
24790604
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Public health/Health science
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Research Institution | Hirosaki University |
Principal Investigator |
IINO Kaori 弘前大学, 医学(系)研究科(研究院), 助教 (40568896)
|
Project Period (FY) |
2012-04-01 – 2015-03-31
|
Project Status |
Completed (Fiscal Year 2014)
|
Budget Amount *help |
¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
Keywords | 骨粗鬆症 / FRAX / 骨折リスク / 骨粗しょう症 / スクリーニング / 骨折率 |
Outline of Final Research Achievements |
FRAX was developed by WHO for the evaluation of fracture risk of patients based on individual patient model after integrating the risks associated with clinical risk factors. This study was to compare the fracture probabilities calculated by FRAX with actual fracture rates in the community. The 10-year provability of fracture calculated by FRAX and actual fracture rate were 4.31% and 4.12% for women aged 50-59 years old (N = 95), 8.23% and14.26 % for women aged 60-69 years old (N = 104), and 15.20% and 17.73% for women aged >70 years (N = 41), respectively. Fracture probability calculated from FRAX may be underestimated. Therefore, other risk factor (e.g. marker of bone metabolism) or bone density should be assessed when we use FRAX as a tool of osteoporotic screening.
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Report
(4 results)
Research Products
(2 results)