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An innovative new endoscopic surgical system using fluorescent measurement technology for gastroenterological operation

Research Project

Project/Area Number 25462009
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Digestive surgery
Research InstitutionTohoku University

Principal Investigator

KAMEI TAKASHI  東北大学, 医学(系)研究科(研究院), 准教授 (10436115)

Co-Investigator(Kenkyū-buntansha) NAKAGAWA TOMOHIKO  東北大学, 病院, 医員 (00646804)
GONDA KOUSUKE  東北大学, 大学院医学系研究科, 教授 (80375435)
Ohuchi Noriaki  東北大学, 大学院医学系研究科, 教授 (90203710)
TESHIMA JIN  東北大学, 病院, 医員 (90579749)
Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2014: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2013: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords蛍光プロ―ブ / 蛍光内視鏡手術 / 蛍光クリップ / リアルタイムナビゲーション / 蛍光内視鏡 / 蛍光プローブ / リアルタイムイメージング
Outline of Final Research Achievements

The aim of this research was development of a new fluorescent endoscopic surgical system and we had the study results as below.
1.We created an original organic fluorescent probe and analyzed the property of this particle. This probe had advantages in fluorescent signal intensity and degradation time compared with quantum dot or ICG.2.We developed an original gastrointestinal endoscopic clip with the new fluorescent probe. 3.We developed an original fluorescent endoscopic surgical system and refined the conditions for human application in the future.4.We successfully detected the fluorescent signal of the clips from outside of the gastrointestinal tract in pig model using our original surgical system.5.We performed analysis of the fluorescent property and dynamics of the original fluorescent particle in living tissues.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (3 results)

All 2015 2014

All Presentation (3 results)

  • [Presentation] 胸腔鏡下食道癌手術の変遷2015

    • Author(s)
      亀井尚
    • Organizer
      第28回日本内視鏡外科学会
    • Place of Presentation
      大阪市・大阪国際会議場
    • Year and Date
      2015-12-10
    • Related Report
      2015 Annual Research Report
  • [Presentation] 胸部食道癌に対する鏡視下手術の手技と工夫2015

    • Author(s)
      亀井尚
    • Organizer
      第77回日本臨床外科学会
    • Place of Presentation
      福岡市・福岡国際会議場
    • Year and Date
      2015-11-26
    • Related Report
      2015 Annual Research Report
  • [Presentation] 胸腔鏡下食道切除術の発展に向けて-手術手技、機器の進歩2014

    • Author(s)
      亀井尚
    • Organizer
      第69回日本消化器外科学会
    • Place of Presentation
      郡山市(郡山市民文化センター)
    • Year and Date
      2014-07-16 – 2014-07-18
    • Related Report
      2014 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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