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The Effects of Adrenaline and Vasopressin onPial Microvessels During Global Brain Ischemia-reperfusion Period in Rabbits.

Research Project

Project/Area Number 25462401
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Anesthesiology
Research InstitutionUniversity of Yamanashi

Principal Investigator

ASANO Nobumasa  山梨大学, 総合研究部, 助教 (30456470)

Co-Investigator(Renkei-kenkyūsha) ISHIYAMA Tadahiko  山梨大学, 総合研究部, 准教授 (90293448)
MASAMUNE Taishi  山梨大学, 総合研究部, 助教 (40324199)
IWASHITA Hironobu  山梨大学, 総合研究部, 助教 (10232670)
KOTODA Masakazu  山梨大学, 総合研究部, 助教 (30530133)
IKEMOTO Koudai  山梨大学, 総合研究部, 助教 (50530127)
KUMAKURA Yasutomo  山梨大学, 総合研究部, 助教 (00530130)
Project Period (FY) 2013-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2014: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2013: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Keywordscranial window / cranial window / adorenaline / landiool / adrenaline / vasopressin
Outline of Final Research Achievements

Adrenaline and Vasopressin were recommended to use during cardiopulmonary resuscitation. The aims of the present study were to evaluate the direct effects of adrenaline and vasopressin on cerebral pial arterial diameter changes in the normal states and during ischemia-reperfusion period.
Adrenaline and Vasopressin exerted no direct action on cerebral pial artery in the normal state. Adrenaline increased cerebral pial arteriolar diameter at compared with vasopressin and control in the ischemia-reperfusion period.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (4 results)

All 2015 2014 2013 Other

All Presentation (3 results) Remarks (1 results)

  • [Presentation] The effects of Landiolol on pial microvesseles during global brain ischemia-reperfusion period in rabbits2015

    • Author(s)
      浅野 伸将
    • Organizer
      anesthesiology 2015, Annual meeting
    • Place of Presentation
      アメリカ、サンディエゴ
    • Year and Date
      2015-10-24
    • Related Report
      2015 Research-status Report
  • [Presentation] 脳血管に対するアドレナリンの直接的効果の検討 -cranial window-法を用いて2014

    • Author(s)
      浅野伸将、鈴木翔、石山忠彦
    • Organizer
      第18回日本神経麻酔・集中治療研究会
    • Place of Presentation
      沖縄県那覇市 ANAクラウンプラザホテル沖縄ハーバービュー、沖縄県市町村自治会館
    • Related Report
      2013 Research-status Report
  • [Presentation] The Effects of vasopressin on Pial Microvessels During Global Brain Iscemia-reperfusion Period in Rabbits2013

    • Author(s)
      浅野伸将、石山忠彦、古藤田正和、正宗大士、池本剛大、松川隆
    • Organizer
      Anesthesiology 2013 Annual Meeting
    • Place of Presentation
      アメリカ、サンフランシスコ モスコンセンター
    • Related Report
      2013 Research-status Report
  • [Remarks] 山梨大学医学部麻酔科学講座脳循環実験グループ

    • URL

      http://y-anesth.jp/research/nou/

    • Related Report
      2016 Annual Research Report

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Published: 2014-07-25   Modified: 2019-07-29  

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