Development of fundamental therapy for temporomandibular muscle disorders by gastroenterological approach.
| Project/Area Number |
25463191
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Orthodontics/Pediatric dentistry
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| Research Institution | Kagoshima University |
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Principal Investigator |
Takada Hiroko 鹿児島大学, 医歯学総合研究科, 客員研究員 (80634229)
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| Co-Investigator(Kenkyū-buntansha) |
大牟禮 治人 鹿児島大学, 医歯学総合研究科, 客員研究員 (00404484)
永山 邦宏 鹿児島大学, 医歯学域附属病院, 助教 (60583458)
宮脇 正一 鹿児島大学, 医歯学域歯学系, 教授 (80295807)
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| Project Period (FY) |
2013-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 咀嚼 / 消化管ホルモン / 咀嚼筋障害 / 消化管運動 / 歯科矯正学 |
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| Outline of Final Research Achievements |
Gastrointestinal hormones and 13C-acetate breath test with electrogastrography and electrocardiography was performed in healthy men who ingested a test meal with or without chewing gum. Blood samples for the measurement of glucose, insulin, gastrin, ghrelin, CCK, and GLP-1 were drawn before the meal and at 30-min intervals after the beginning of test meal consumption until the end of the session 240 min later. As a result, no significant difference in gastrointestinal hormones was observed between the two trials in 4 healthy men.
A causal relationship between gastrointestinal hormones and temporomandibular muscle disorders was not determined in this study and should be investigated in future studies.
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Report
(5 results)
Research Products
(2 results)
