Bone regeneration by combination with human iPS cells and FGF18 in bone microenvironment-imitated Scaffold
| Project/Area Number |
25893157
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Surgical dentistry
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| Research Institution | The University of Tokushima |
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Principal Investigator |
KOBAYASHI Masako 徳島大学, ヘルスバイオサイエンス研究部, 助教 (90706954)
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| Project Period (FY) |
2013-08-30 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | iPS細胞 / 骨再生 / FGF / スキャフォールド / hiPSC / FGF18 / 骨芽細胞 |
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| Outline of Final Research Achievements |
We focused on human induced Pluripotent Stem (iPS) cells, Fibroblast growth factors, and carbonate apatite as a scaffold in order to realize ideal bone tissue formation for bone regenerative medicine. Implantation of iPS cells with either carbonate apatite granules, calcium carbonate granules, or β-TCP granules to nude mice showed that bone like-structure surrounding the granules could be observed in carbonate apatite group and calcium carbonate group.
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Report
(3 results)
Research Products
(3 results)
