A comparative study of resting state functional connectivity MRI and intracranial EEG for epilepsy surgery
| Project/Area Number |
26462216
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Neurosurgery
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| Research Institution | Wakayama Medical University |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2016: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2015: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2014: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
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| Keywords | てんかん / 機能的MRI / 機能的結合 / 頭蓋内脳波 / 発作焦点 / functional connectivity / 安静時機能的MRI / 難治化 / てんかん原性領域 / 脳機能再構築 / 安静時機能的ＭＲＩ / 発作型 |
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| Outline of Final Research Achievements |
Resting-state functional connectivity magnetic resonance imaging (rs-fcMRI) were applied for pre-surgical evaluation of patients who underwent resective surgery via intracranial EEG. Reduced network centrality was prominent in ictal onset zones by voxel-to-voxel analysis. Sequential alteration of functional connectivity was analyzed by selecting remnant epileptic focus as a region of interest using seed-to voxel analysis. Imaging findings of rs-fcMRI altered according to clinic-encephalographic state. Rs-fcMRI is a useful tool even for an individual epileptic patient to explore epileptic focus and estimate clinical condition.
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Report
(4 results)
Research Products
(8 results)
