The effect of ultraviolet functionalization of titanium on inflammation control
| Project/Area Number |
26462980
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Dental engineering/Regenerative dentistry
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| Research Institution | Nihon University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
萩原 芳幸 日本大学, 歯学部, 准教授 (00228389)
本田 和也 日本大学, 歯学部, 教授 (30199567)
池田 貴之 日本大学, 歯学部, 講師 (30366603)
本田 雅規 愛知学院大学, 歯学部, 教授 (70361623)
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| Co-Investigator(Renkei-kenkyūsha) |
ARAI Yoshinori 日本大学, 歯学部, 教授 (20212607)
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| Research Collaborator |
OGAWA Takahiro
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | チタン / インプラント / オッセオインテグレーション / 紫外線 / マクロファージ |
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| Outline of Final Research Achievements |
In this present study, we evaluated the effect of UV treatment of titanium on the cellular reaction of macrophage. The amount of TNF-α in the supernatant of an untreated group was higher than that of UV treated group. In contrast, UV treatment increased the expression of IL-10 in the supernatant compared to untreated group. UV treatment decreased the number of CD48+ cells attached to titanium surface compared to the untreated surface. The results suggest that a surface alteration using UV-light treatment affect a cellular behavior of macrophage.
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Report
(4 results)
Research Products
(1 results)
