Effect of chemerin and chemerin reteptor on development of ruminant skeletal muscle

Research Project

Project/Area Number	26850169
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Multi-year Fund
Research Field	Animal production science
Research Institution	Shimane University
Principal Investigator	SONG SANG HOUN 島根大学, 生物資源科学部, 助教 (50617074)
Project Period (FY)	2014-04-01 – 2016-03-31
Project Status	Completed (Fiscal Year 2015)
Budget Amount *help	¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000) Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000) Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords	ケメリン / ケメリン受容体 / 反芻動物 / 筋発達 / chemerin / CMKR1 / 筋牙細胞 / 脂肪細胞分化 / 筋細胞分化
Outline of Final Research Achievements	The aim of this study was to investigate the effect of chemerin and chemerin receptor on development of ruminant skeletal muscle. <Results> 1)adipocyte chemerin mRNA expression was changed by induction of lipid accumulation. 2) chemerin receptor and chemerin regulated differentiation and proliferation of ruminant myocytes. 3)mRNA expression of chemerin receptor was changed during the fattening period. These results suggest that chemerin regulates the development of ruminant skeletal muscle via chemerin receptor.

Report

(3 results)