Dissection and Regulation of Plant Function with Synthetic Molecules

2021 Fiscal Year Final Research Report

• Project Area: Chemical Approaches for Miscellaneous / Crowding Live Systems
• Project/Area Number: 17H06350
• Research Category: Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
• Allocation Type: Single-year Grants
• Review Section: Science and Engineering
• Research Institution: Institute of Physical and Chemical Research (2018-2021); Nagoya University (2017)
• Principal Investigator: Hagihara Shinya 国立研究開発法人理化学研究所, 環境資源科学研究センター, チームリーダー (80373348)
• Project Period (FY): 2017-06-30 – 2022-03-31
• Keywords: 植物ホルモン / ケミカルバイオロジー

Outline of Final Research Achievements

Molecular recognition in miscellaneous and crowding multimolecular biosystems plays an important role in biological functions. Especially, the specific interaction between plant hormone and its receptor protein is crucial for long-distance signal transduction that enables plants to rapidly adapt to environmental changes. Although recent biological studies have made substantial progress in our understanding of plant hormone signaling, delineating plant hormone response at molecular level remains a major challenge. So far, we have developed chemistry-based approaches to understand and regulate auxin signaling. In this project, we applied the identical approach to regulate cytokinin and gibberellin signaling. The technology developed in this project should provide a key methodology that anables sustainable agriculture.

Free Research Field

植物ケミカルバイオロジー

Academic Significance and Societal Importance of the Research Achievements

植物の多様な生理機能の多くは、植物ホルモンによって制御されている。植物ホルモンの作用を細胞や器官レベルで制御する手法は、植物の生理機能解明だけでなく、農作業の手間を劇的に軽減する可能性をもっている。我々が今回開発した技術は、内在性の植物ホルモンとは独立してシグナルをオンにすることが可能で、これを活用すれば、望みの器官や細胞で植物ホルモンの効果を発現することができる。