Isolation of genes expressed asymmetrically in flounder metamorphosis and regulation by thyroid hormone

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K07571
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Aquatic life science
• Research Institution: Tohoku University
• Principal Investigator: Yokoi Hayato 東北大学, 農学研究科, 助教 (40569729)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: ヒラメ / 変態 / 異体類 / 次世代シーケンサー

Outline of Final Research Achievements

Flounder transform their body plan during metamorphosis; right eye migrates to the other side and pigment cells differentiate only in the ocular side. Gene expression profile were compared between ocular and blind side in tissues around supra orbital bar at early metamorphic stage and skin and muscle tissue at later metamorphic stage in order to isolate genes expressed asymmetrically between ocular and blind side. Candidate genes were further analyzed by in situ hybridization and suggested that genes might be involved in right side specific degeneration of supra orbital bar and genes that genes might be involved in ocular side specific pigment cell differentiation.

Free Research Field

マリンゲノミクス