the effect of a modified Glenn shunt for the right ventricular failure under the left ventricular assist device support

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K10030
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: General surgery
• Research Institution: Kyushu University
• Principal Investigator: TANOUE YOSHIHISA 九州大学, 医学研究院, 准教授 (40372742)
• Co-Investigator(Kenkyū-buntansha): 鬼塚 大史 九州大学, 大学病院, 医員 (20567375) ; 元松 祐馬 九州大学, 医学研究院, 共同研究員 (20746870) ; 帯刀 英樹 九州大学, 大学病院, 講師 (40343321) ; 塩川 祐一 九州大学, 医学研究院, 准教授 (70457422) ; 牛島 智基 九州大学, 大学病院, 助教 (70529875)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 重症心不全 / 左心補助人工心臓 / 右心不全 / 右心バイパス

Outline of Final Research Achievements

We considered if a modified Glenn shunt improves haemodynamics in right ventricular failure after a left ventricular assist device (LVAD).Without cardiopulmonary bypass, a modified Glenn shunt was created by connecting the superior vena cava with the main pulmonary artery with a graft with partial clamps on vessel. When we were creating the shunt, ventricular fibrillation (Vf) was induced and was uncontrolled.
We also tried to make a model of left ventricular failure by the ligation of the left main trunk or left anterior descending coronary artery, but failed in controlling Vf.

Free Research Field

心臓血管外科学