Role of apelin on mechanisms to improve state of periodontitis by physical activity and its application to preventive dentistry

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K11423
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Social dentistry
• Research Institution: Kyushu Dental College
• Principal Investigator: Akifusa Sumio 九州歯科大学, 歯学部, 教授 (40295861)
• Co-Investigator(Kenkyū-buntansha): 有吉 渉 九州歯科大学, 歯学部, 准教授 (40405551) ; 臼井 通彦 九州歯科大学, 歯学部, 准教授 (10453630) ; 沖永 敏則 九州歯科大学, 歯学部, 講師 (60582773)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 身体活動 / apelin

Outline of Final Research Achievements

We investigated relationship between physical activity and oral health status in older adults by follow-up survey. The cohort of older adults with dysphagia at baseline deteriorated physical activity and nutritional status at 1 years later, comparing with the cohort having normal swallowing function. Mortality risk of older adults with > 9 remained tooth and dysphagia was 2.89-fold higher than that of older adults > 10 remained tooth and with normal swallowing function. Next we elucidated the peak expiratory flow (PEF), having closing relation with physical activity, in older adults who were intervened with oral care with tongue cleaning. The PEFs of older adults intervened by oral care with tongue cleaning was significantly higher than of those without tongue cleaning. Unfortunately, we could get no significant data on relationship between amounts of blood apelin and PEF.

Free Research Field

口腔衛生学