Development of a novel type of carbohydrate probes

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K12760
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Chemical biology
• Research Institution: Kyushu University (2016-2017); Institute of Physical and Chemical Research (2015)
• Principal Investigator: Hirai Go 九州大学, 薬学研究院, 教授 (50359551)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 複合糖質 / シアリダーゼ / 酵素反応 / 分子プローブ

Outline of Final Research Achievements

Carbohydrates (glycoconjugates) have important functions. Degradation of carbohydrates that play a role of "turning off" functions of original carbohydrates, is also important process in cells. However, it is not possible to monitor when or which enzymes degradate a specific glycoconjugate in cells. This time, a new molecular tool that can do this was successfully developed with our own idea.

Free Research Field

ケミカルバイオロジー　有機合成化学