VATS lobectomy under HELIOX inhalation

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K15518
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Respiratory surgery
• Research Institution: Wakayama Medical University
• Principal Investigator: Kokawa Yozo 和歌山県立医科大学, 医学部, 博士研究員 (30336888)
• Co-Investigator(Kenkyū-buntansha): 吉増 達也 和歌山県立医科大学, 医学部, 准教授 (60316099)
• Research Collaborator: YOSHIMASU TATSUYA 和歌山県立医科大学, 医学部, 准教授 (60316099)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 肺癌 / 胸腔鏡手術 / ヘリウムガス

Outline of Final Research Achievements

Heliox is a breathing gas composed of a mixture of helium and oxygen and is used when diving. In order to verify whether Heliox ventilation promotes surgical side pulmonary collapse, a randomized phase II study was performed on lung cancer patients who underwent thoracoscopic surgery. 18 cases were Heliox inhalated ventilation (group H) and 15 cases were normal ventilated group (group C). The visual field was secured (VG) and the degree of collapse of the lung (AG) were evaluated in 5 stages respectively.
There were no significant differences in H group and C group among age, gender, operation type, lesion occupation site, preoperative respiratory function.
There were no significant differences in H group and C group among VG, AG, operation time, bleeding volume, postoperative hospital stay days, drainage period, drain total waste volume, intraoperative SpO2 minimum value, postoperative SpO2 lowest value, postoperative white blood cell maximum value, postoperative CRP maximum value.

Free Research Field

呼吸器外科