Charange to regenerate the periodontal ligament using mouse tooth re-plantation model

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K15762
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Orthodontics/Pediatric dentistry
• Research Institution: Fukuoka Dental College
• Principal Investigator: OKA KYOKO 福岡歯科大学, 口腔歯学部, 准教授 (60452778)
• Co-Investigator(Kenkyū-buntansha): 敦賀 英知 弘前大学, 保健学研究科, 教授 (30295901)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 歯の外傷 / 歯根発生 / 歯根膜再生

Outline of Final Research Achievements

Avulsion is the severest type of dental trauma. The prognosis depends on the success of periodontal ligament regeneration after re-plantation. In re-plantation of an avulsed tooth, it has been thought that the viability of periodontal ligament cells on the root surface is a critical factor for PDL regeneration. We examined about mechanism of root development and regeneration of periodontal ligament tissue. For the clinical success of tooth re-plantation, we established ''mouse tooth re-plantation model'', and investigate the effect of artificial material for periodontal ligament tissue regeneration.

Free Research Field

顔面発生