Experiment to perform nerve reproduction by using mononuclear leukocyte derived from the marrow which gathered with artificial nerve tube (PGA-C Tube)

2017 Fiscal Year Final Research Report

• Project/Area Number: 16K15820
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Surgical dentistry
• Research Institution: Kyoto University
• Principal Investigator: Shigeno Keiji 京都大学, ウイルス・再生医科学研究所, 非常勤講師 (00162587)
• Co-Investigator(Kenkyū-buntansha): 中村 達雄 京都大学, ウイルス・再生医科学研究所, 准教授 (70227908)
• Project Period (FY): 2016-04-01 – 2018-03-31
• Keywords: trigeminal nerve / maxillofacial / PGA-C-tube / CRPS / mononuclear leukocyte

Outline of Final Research Achievements

The trigeminal nerve of the maxillofacial have been considered that reproduction was difficult until now. In contrast, the synthetic high polymer + collagen composite material (PGA-C-tube that we developed it newly: Neuropathic sharp pain ((Seo K, Periph Nerve 26:2,015 which reported that good recovery was provided for so-called CRPS)) that was taking place for the trigeminal nerve damage using technique of artificial neural tube) and in situ Tissue Engineering. It was earlier and regenerated the trigeminal nerve of the maxillofacial closely by using mononuclear leukocyte derived from the self-marrow which I hid possibility to promote a reproduction power in together based on these results and knew that early healing was got.

Free Research Field

再生医工学