2017 Fiscal Year Final Research Report
Application of antimicrobial-rechargeable polymer particles to denture base resins
| Project/Area Number |
16K20497
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Prosthodontics/ Dental materials science and
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| Research Institution | Osaka University |
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Principal Investigator |
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| Project Period (FY) |
2016-04-01 – 2018-03-31
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| Keywords | 抗菌性 / 薬剤徐放 / ポリマー / 義歯 |
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| Outline of Final Research Achievements |
In this study, cetylpyridinium chloride (CPC)-loaded polymer particles, that can release CPC continuously by recharging, were incorporated into a commercial PMMA denture base resin, and their CPC-recharge profiles, antifungal properties, and flexural strengths were evaluated in vitro. Incorporation of CPC-loaded polymer particles at 20(wt)% was effective to maintain CPC-release from the PMMA resin by recharging, and achieve inhibitory effects against adherence of C. albicans on the surface, without hampering the flexural strength of resin.
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| Free Research Field |
歯科生体材料学
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