2009 Fiscal Year Final Research Report
Asbestos related pleural malignant mesothelioma-18F-FDG PET/CT findings-
| Project/Area Number |
19591440
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Kurume University |
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Principal Investigator |
KURATA Seiji Kurume University, 医学部, 助教 (80268888)
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| Co-Investigator(Kenkyū-buntansha) |
KAIDA Hayato 久留米大学, 医学部, 助教 (40299425)
ISHIBASHI Masatoshi 久留米大学, 医学部, 教授 (20168256)
HAYABUCHI Naofumi 久留米大学, 医学部, 教授 (20108731)
TAKAMORI Shinzo 久留米大学, 医学部, 准教授 (50197208)
AIZAWA Hisamichi 久留米大学, 医学部, 教授 (90175711)
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| Project Period (FY) |
2007 – 2009
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| Keywords | PET / CT / アスベスト / 悪性胸膜中皮腫 |
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| Research Abstract |
Analysis of 18F-FDG PET/CT and plasma osteopontin levels were performed in asbestos-related pleural disease patients. Six patients had histologically proven malignant pleural mesothelioma (MPM). In 11 patients, the disease was considered benign pleural disease. Four patients had proven asbestos pleurisy. The remaining 7 patients had proven pleural plaques. Significant differences were found among the three groups of asbestos-related pleural diseases for the plasma osteopontin levels and the SUVmax. Significant differences in the SUVmax were found between patients with MPM and those with asbestos pleurisy and between patients with MPM and patients with pleural plaques. However, there was no significant difference in the plasma osteopontin levels between patients with MPM and patients with asbestos pleurisy or between patients with MPM and patients with pleural plaques. The SUVmax in patients with benign asbestos-related diseases correlated well with plasma osteopontin levels in the same group, but the SUVmax in patients with MPM did not correlate with plasma osteopontin levels in the same group. PET/CT might be more helpful in distinguishing benign asbestos-related pleural diseases from MPM than plasma osteopontin, and the SUVmax in benign asbestos-related pleural diseases may reflect changes in pleural inflammation.
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Research Products
(10 results)
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[Journal Article] Prognostic value of SUVmax measurements obtained by FDG-PET in patients with non-small cell lung cancer receiving chemotherapy.2010
Author(s)
Yohei Imamura, Koichi Azuma, Seiji Kurata, Satoshi Hattori, Tetsuro Sasada, Takashi Kinoshita, Masaki Okamoto, Tomotaka Kawayama, Hayato Kaida, Masatoshi Ishibashi, Hisamichi Aizawa.
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Journal Title
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[Journal Article] Improved breast cancer detection of prone breast fluorodeoxyglucose-PET in 118 patients Nuclear Medicine Communications2008
Author(s)
Hayato Kaida, Masatoshi Ishibashi, Teruhiko Fujii, Seiji Kurata, Masafumi Uchida, Kenkichi Baba, Teruo Miyagawa, Hiroko Kaibara, Seiji Kawamura, Etsuyo Ogo, Naofumi Hayabuchi.
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Journal Title
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[Presentation] Naofumi Hayabuchi Staging of mediastinal and hilar lymph node metastases from nonsmall cell lung cancer:comparison of diagnosis accuracy of MRI and FDG-PET 13th World Conference on Lung Cancer2009
Author(s)
Kiminori Fujimoto, Hayato Kaida, Nestor L. Muller, Junko Sadohara, Ryouji Iwamoto, Naoko Fujimoto, Seiji Kurata, Fumihiko Muta, Toshihiro Matsuo, Shinzo Takamori, Masatoshi Ishibashi
Place of Presentation
San Francisco, U.S. A
Year and Date
20090731-20090804
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[Presentation] FDG-PETと分子病理学的手法を用いての甲状腺乳頭癌の細胞増殖能の特性解析2008
Author(s)
甲斐田勇人, 石橋正敏, 倉田精二, 小林真衣子, 貝原紘子, 早渕尚文, 広松雄治, 三橋拓之, 梅野博仁, 中島格, 河原明彦, 鹿毛政義
Organizer
第48回日本核医学会学術総会
Place of Presentation
幕張メッセ
Year and Date
20081024-20081026
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