2021 Fiscal Year Final Research Report
A production method of Tc-99m medical radioactive isotopes by hot atoms and hydrated MoO3 porous targets
| Project/Area Number |
19H02429
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Review Section |
Basic Section 26020:Inorganic materials and properties-related
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| Research Institution | Nagaoka University of Technology |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
鈴木 達也 長岡技術科学大学, 工学研究科, 教授 (70323839)
南口 誠 長岡技術科学大学, 工学研究科, 教授 (90272666)
Do T.M.Dung 長岡技術科学大学, 工学研究科, 助教 (90638420)
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| Project Period (FY) |
2019-04-01 – 2022-03-31
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| Keywords | 医療用放射性同位体 / ホットアトム |
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| Outline of Final Research Achievements |
Alfa-MoO3 porous sintered bodies, alfa-MoO3 dendrites and beta-MoO3 whiskers were prepared and irradiated by neutrons. After the irradiation, they were dispersed in water. beta-MoO3 whiskers showed the highest recovery ratio of Mo-99 into water of 67%. These results were thought to be caused by the long Mo-O interlayer distance, the hydration property and the short width of beta- MoO3 whiskers, in which water and 99Mo can easily diffuse. In this research, a novel Mo-99 production method only disperse the neutron irradiated target in water has been developed.
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| Free Research Field |
材料科学
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| Academic Significance and Societal Importance of the Research Achievements |
本研究により、高温濃NaOH溶液へのターゲット溶解での潜在的危険性や、Mo-98からMo-99の同位体分離技術の開発なしに、中性子照射したβ- MoO3ウイスカーターゲットを水に分散・フィルター濾過するだけでMo-99水溶液を抽出する技術の開発に成功した。これにより、Mo-99とその娘核種であるTc-99mの医療用放射性同位体製剤の、国内安定供給法確立に道を拓いた。本技術は、高濃縮U-235燃料を用いた原子炉を必要とせず、世界の核拡散防止にも大きな貢献が可能と考えられる。
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