Development of short version of fatigue impact scale for patients with systemic lupus erythematosus

2022 Fiscal Year Final Research Report

• Project/Area Number: 19K10944
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Review Section: Basic Section 58060:Clinical nursing-related
• Research Institution: Osaka University (2022); Konan Women's University (2019-2021)
• Principal Investigator: Makimoto Kiyoko 大阪大学, 大学院医学系研究科, 名誉教授 (80262559)
• Co-Investigator(Kenkyū-buntansha): 井上 満代 兵庫医療大学, 看護学部, 准教授 (70803667) ; 周藤 俊治 奈良県立医科大学, 医学部, 准教授 (30420748)
• Project Period (FY): 2019-04-01 – 2023-03-31
• Keywords: SLE / 疲労感 / 症状管理 / 症状の変動 / 運動量 / 睡眠の質 / QoL / 疼痛

Outline of Final Research Achievements

The purpose of the study was to develop a shorter version of Fatigue Impact Scale to measure changes in daily fatigue level in patients with systemic lupus erythematosus. A pilot study was conducted to measure physical activity and quality of sleep using monitoring devices for 4 weeks with self-reported fatigue and pain levels in 20 participants. Daily moderate to vigorous activity level and several quality of sleep indicators were associated with fatigue level. Regarding daily fatigue impact scale development, 153 patients with SLE outpatients participanted in the data collection using Fatigue Impact Scale, LupusPro, SF-12, and Pittsburge Sleel Scale.

Free Research Field

看護疫学

Academic Significance and Societal Importance of the Research Achievements

疲労感は、原因が不明で、生物学的指標も同定されておらず、疲労感に悩む患者以外からは理解しにくい症状である。このため主治医や家族でも疲労感の日常生活への影響は理解されにくい。本研究では、疲労感を簡便に毎日記録できる尺度の開発により、疲労に関連した運動レベルや睡眠指標の測定、行動記録など疲労のトリガーとなる要因を同定することに貢献することが期待される。